Titre : | Cocaine intoxication (2012) |
Auteurs : | J. L. ZIMMERMAN |
Type de document : | Article : Périodique |
Dans : | Critical Care Clinics (Vol.28, n°4, October 2012) |
Article en page(s) : | 517-526 |
Langues: | Anglais |
Discipline : | PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods) |
Mots-clés : |
Thésaurus mots-clés COCAINE ; VOIE D'ADMINISTRATION ; EFFET SECONDAIRE ; INTOXICATION ; PHARMACOLOGIE ; PHYSIOLOGIE ; SYSTEME NERVEUX CENTRAL ; APPAREIL CARDIOVASCULAIRE ; APPAREIL RESPIRATOIRE ; SYMPTOME ; TOXICITE |
Résumé : | Cocaine, a natural alkaloid derived from the coca plant, is one of the most commonly abused illicit drugs. Cocaine is commonly abused by inhalation, nasal insufflation, and intravenous injection, resulting in many adverse effects that ensue from local anesthetic, vasoconstrictive, sympathomimetic, psychoactive, and prothrombotic mechanisms. Cocaine can affect all body systems and the clinical presentation may primarily result from organ toxicity. Among the most severe complications are seizures, hemorrhagic and ischemic strokes, myocardial infarction, aortic dissection, rhabdomyolysis, mesenteric ischemia, acute renal injury and multiple organ failure. |
Domaine : | Drogues illicites / Illicit drugs |
Sous-type de document : | Revue de la littérature / Literature review |
Refs biblio. : | 61 |
Affiliation : | Department of Medicine, Weill Cornell Medical College, New York, NY, USA |
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