Article de Périodique
Prevalence of hepatitis B and hepatitis C virus infections in France in 2004: social factors are important predictors after adjusting for known risk factors (2010)
Auteur(s) :
MEFFRE, C. ;
LE STRAT, Y. ;
DELAROCQUE-ASTAGNEAU, E. ;
DUBOIS, F. ;
ANTONA, D. ;
LEMASSON, J. M. ;
WARSZAWSKI, J. ;
STEINMETZ, J. ;
COSTE, D. ;
MEYER, J. F. ;
LEISER, S. ;
GIORDANELLA, J. P. ;
GUEGUEN, R. ;
DESENCLOS, J. C.
Année :
2010
Page(s) :
546-555
Langue(s) :
Anglais
Domaine :
Drogues illicites / Illicit drugs
Discipline :
MAL (Maladies infectieuses / Infectious diseases)
Thésaurus géographique
FRANCE
Thésaurus mots-clés
HEPATITE
;
PREVALENCE
;
INFECTION
;
FACTEUR DE RISQUE
;
ETUDE TRANSVERSALE
;
FACTEUR PREDICTIF
;
ANALYSE CHIMIQUE
;
TEST
;
INJECTION
Résumé :
To monitor the prevalence of hepatitis B and hepatitis C a cross-sectional survey was conducted in 2004 among French metropolitan residents. A complex sampling design was used to enroll 14,416 adult participants aged 18-80 years. Data collected included demographic and social characteristics and risk factors. Sera were tested for anti-HCV, HCV-RNA, anti-HBc and HBsAg. Data were analyzed with SUDAAN software to provide weighted estimates for the French metropolitan resident population. The overall anti-HCV prevalence was 0.84% (95% CI: 0.65-1.10). Among anti-HCV positive individuals, 57.4% (95% CI: 43.2-70.5) knew their status. Factors associated independently with positive anti-HCV were drug use (intravenous and nasal), blood transfusion before 1992, a history of tattoos, low socioeconomic status, being born in a country where anti-HCV prevalence >2.5%, and age >29 years. The overall anti-HBc prevalence was 7.3% (95%: 6.5-8.2). Independent risk factors for anti-HBc were intravenous drug use, being a man who has sex with men, low socioeconomic status, a stay in a psychiatric facility or facility for the mentally disabled, 2%, age >29 and male sex. The HCV RNA and HBsAg prevalence were 0.53% (95% CI: 0.40-0.70) and 0.65% (95% CI: 0.45-0.93), respectively. Among HBsAg positive individuals, 44.8% (95% CI: 22.8-69.1) knew their status. Anti-HCV prevalence was close to the 1990s estimates whereas HBsAg prevalence estimate was greater than expected. Screening of hepatitis B and C should be strengthened and should account for social vulnerability.
Affiliation :
National Institute for Public Health Surveillance (InVS), Saint-Maurice, France