Historique
Article de Périodique
The recreational tryptamine 5-MeO-DALT (N,N-diallyl-5-methoxytryptamine): A brief review (2012)
Auteur(s) :
J. M. CORKERY ;
E. DURKIN ;
S. ELLIOTT ;
F. SCHIFANO ;
A. H. GHODSE
Dans :
Progress in Neuro-Psychopharmacology and Biological Psychiatry (Vol.39, n°2, 3 December 2012)
Article en page(s) :
259-262
Sous-type de document :
Revue de la littérature / Literature review
Domaine :
Drogues illicites / Illicit drugs
Langue(s) :
Anglais
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus géographique
ROYAUME-UNI
Thésaurus mots-clés
DROGUES DE SYNTHESE
;
ANALYSE CHIMIQUE
;
PHARMACOLOGIE
;
EFFET SECONDAIRE
;
TOXICITE
;
MORTALITE
;
TOXICOLOGIE
Résumé :
5-MeO-DALT (N,N-diallyl-5-methoxytryptamine) is a psychoactive substance, sold primarily over the Internet as a 'research chemical' or 'plant food'. Although details for the synthesis of this tryptamine have been available since 2004, its use as a hallucinogenic drug has been reported only occasionally in on-line user fora. It is controlled in only a few countries world-wide. There is little scientifically-based literature on the pharmacological, physiological, psychopharmacological, toxicological and epidemiological characteristics of 5-MeO-DALT. Here we review what is known about these aspects. We also report what we believe to be the first death involving the use of this substance. The case involved a man in his mid-20s who died in mid-2010. The coroner concluded that the deceased "died from injuries sustained after being hit by a lorry whilst under the influence of 5-MeODALT". It is critical that any other cases, including non-fatal instances, are documented so that a scientific evidence-base can be established for this drug.
HIGHLIGHTS:
• 5-MeO-DALT is a psychoactive substance sold as a 'research chemical'.
• Use as a hallucinogenic is reported by user fora; it can affect risk assessment.
• Scant scientific literature on physical effects, psychopharmacology, toxicology.
• Victim died from injuries sustained when hit by a vehicle whilst under its influence.
• Any (non-) fatal cases need documenting to establish scientific evidence-base.
HIGHLIGHTS:
• 5-MeO-DALT is a psychoactive substance sold as a 'research chemical'.
• Use as a hallucinogenic is reported by user fora; it can affect risk assessment.
• Scant scientific literature on physical effects, psychopharmacology, toxicology.
• Victim died from injuries sustained when hit by a vehicle whilst under its influence.
• Any (non-) fatal cases need documenting to establish scientific evidence-base.
Affiliation :
National Programme for Substance Abuse Deaths (np-SAD), International Centre for Drug Policy, St George's, University of London, London, UK