Historique
Article de Périodique
Cannabis use and vulnerability for psychosis in early adolescence - A TRAILS study (2013)
Auteur(s) :
M. F. H. GRIFFITH-LENDERING ;
J. T. W. WIGMAN ;
A. PRINCE VAN LEEUWEN ;
S. C. J. HUIJBREGTS ;
A. C. HUIZINK ;
J. ORMEL ;
F. C. VERHULST ;
J. VAN OS ;
H. SWAAB ;
W. A. M. VOLLEBERGH
Article en page(s) :
733-740
Refs biblio. :
52
Domaine :
Drogues illicites / Illicit drugs
Langue(s) :
Anglais
Discipline :
PSY (Psychopathologie / Psychopathology)
Thésaurus mots-clés
TROUBLE BIPOLAIRE
;
CANNABIS
;
PSYCHOSE
;
ADOLESCENT
;
FACTEUR DE VULNERABILITE
;
ETUDE PROSPECTIVE
Thésaurus géographique
PAYS-BAS
Note générale :
Commentary: Cross-lagging cannabis and psychosis vulnerability. Lewis G., Heron J., Zammit S., p. 741-742.
Résumé :
Aims - To examine the direction of the longitudinal association between vulnerability for psychosis and cannabis use throughout adolescence.
Design - Cross-lagged path analysis was used to identify the temporal order of vulnerability for psychosis and cannabis use, while controlling for gender, family psychopathology, alcohol use and tobacco use.
Setting - A large prospective population study of Dutch adolescents [the TRacking Adolescents' Individual Lives Survey (TRAILS) study].
Participants - A total of 2120 adolescents with assessments at (mean) age 13.6, age 16.3 and age 19.1. Measurements - Vulnerability for psychosis at the three assessment points was represented by latent factors derived from scores on three scales of the Youth Self-Report and the Adult Self-Report, i.e. thought problems, social problems and attention problems. Participants self-reported on cannabis use during the past year at all three waves.
Findings - Significant associations (r = 0.12–0.23) were observed between psychosis vulnerability and cannabis use at all assessments. Also, cannabis use at age 16 predicted psychosis vulnerability at age 19 (Z = 2.6, P Conclusions - Cannabis use predicts psychosis vulnerability in adolescents and vice versa, which suggests that there is a bidirectional causal association between the two.
KEY FINDINGS:
Cannabis use predicts psychosis vulnerability among Dutch adolescents, and vice versa.
Design - Cross-lagged path analysis was used to identify the temporal order of vulnerability for psychosis and cannabis use, while controlling for gender, family psychopathology, alcohol use and tobacco use.
Setting - A large prospective population study of Dutch adolescents [the TRacking Adolescents' Individual Lives Survey (TRAILS) study].
Participants - A total of 2120 adolescents with assessments at (mean) age 13.6, age 16.3 and age 19.1. Measurements - Vulnerability for psychosis at the three assessment points was represented by latent factors derived from scores on three scales of the Youth Self-Report and the Adult Self-Report, i.e. thought problems, social problems and attention problems. Participants self-reported on cannabis use during the past year at all three waves.
Findings - Significant associations (r = 0.12–0.23) were observed between psychosis vulnerability and cannabis use at all assessments. Also, cannabis use at age 16 predicted psychosis vulnerability at age 19 (Z = 2.6, P Conclusions - Cannabis use predicts psychosis vulnerability in adolescents and vice versa, which suggests that there is a bidirectional causal association between the two.
KEY FINDINGS:
Cannabis use predicts psychosis vulnerability among Dutch adolescents, and vice versa.
Affiliation :
Department of Clinical Child and Adolescent Studies, Faculty of Social Sciences, Leiden University, Leiden, the Netherlands