|Titre :||Access to care of patients with chronic hepatitis C virus infection in a university hospital: Is opioid dependence a limiting condition? (2009)|
|Auteurs :||V. PERUT ; C. LABALETTE ; P. SOGNI ; I. FERRAND ; D. SALMON-CERON ; G. VIDAL-TRECAN|
|Type de document :||Article : Périodique|
|Dans :||Drug and Alcohol Dependence (Vol.104, n°1-2, September 2009)|
|Article en page(s) :||78-83|
|Discipline :||MAL (Maladies infectieuses / Infectious diseases)|
Thésaurus TOXIBASEHEPATITE ; ACCES AUX SOINS ; HOPITAL ; ETUDE RETROSPECTIVE ; OPIOIDES ; USAGER ; OPIACES ; PRISE EN CHARGE
BACKGROUND: We aimed to examine access to care of opioid-dependent patients with chronic hepatitis C.
METHODS: A standardized form was used to conduct a retrospective survey from 1999 to 2003 in a French university hospital. All HCV RNA positive in- or outpatients who had not had a liver biopsy or anti-HCV treatment were included. Opioid-dependence was defined as active opioid drug use or being on opioid substitution treatment.
RESULTS: The survey included 580 patients; 137 (23.6%) were opioid-dependent. Fewer patients with than without current opioid dependence had had genotyping (40.1% versus 67.7%, p CONCLUSIONS: Genotyping and liver biopsies were performed less frequently on current opioid dependent patients. Absence of genotyping was also independently associated with unemployment and former opioid-dependence. Alcohol consumption or abnormal ALT levels favored access to biopsy. Histological grade strongly conditioned access to anti-HCV treatment.
|Domaine :||Drogues illicites / Illicit drugs|
|Affiliation :||Risk Management and Quality Unit, AP-HP, Hopital Cochin, Paris, France|