Historique
Chapitre
Mephedrone-related fatalities in the United Kingdom: Contextual, clinical and practical issues, pharmacology
Auteur(s) :
CORKERY, J. M. (Auteur) ;
SCHIFANO, F. (Auteur) ;
GHODSE, A. H. (Auteur) ;
GALLELLI, L. (Éditeur scientifique)
Année :
2012
Page(s) :
355-380
Langue(s) :
Anglais
Éditeur(s) :
Rijeka [Croatia] : InTech
ISBN :
978-953-51-0222-9
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus géographique
ROYAUME-UNI
Thésaurus mots-clés
MEPHEDRONE
;
MORTALITE
;
USAGE RECREATIF
;
DROGUES DE SYNTHESE
;
PHARMACOLOGIE
;
TYPE D'USAGE
;
EFFET SECONDAIRE
Note générale :
In: Pharmacology, Gallelli L. (Ed.), Rijeka: InTech
Résumé :
The misuse of mephedrone (4-methylmethcathinone) has been increasing greatly in Western countries over the last two years or so, especially in the club and dance scenes. This period has also been marked by claims that the substance has been implicated in a rising number of deaths in the USA and Western Europe, especially the United Kingdom (UK).
This chapter explores the context(s) and evolution of mephedrone use in the UK, and the circumstances in which these fatalities occurred. Particular attention is paid to the settings in which these incidents took place, their symptomatology and physical characteristics; intervention/treatment opportunities; and toxicological and pathological findings. These results are related to the known pharmacological facts regarding mephedrone, its possible interactions with alcohol and other psychoactive drugs, and suggested clinical interventions and treatment(s).
The relationship between mephedrone, other methcathinones, and other emerging novel psychoactive substances, as well as established stimulants is also examined. These developments are important as novel substances used for recreational use become more globally accessible through the use of the Internet.
This chapter explores the context(s) and evolution of mephedrone use in the UK, and the circumstances in which these fatalities occurred. Particular attention is paid to the settings in which these incidents took place, their symptomatology and physical characteristics; intervention/treatment opportunities; and toxicological and pathological findings. These results are related to the known pharmacological facts regarding mephedrone, its possible interactions with alcohol and other psychoactive drugs, and suggested clinical interventions and treatment(s).
The relationship between mephedrone, other methcathinones, and other emerging novel psychoactive substances, as well as established stimulants is also examined. These developments are important as novel substances used for recreational use become more globally accessible through the use of the Internet.
Affiliation :
School of Pharmacy, University of Hertfordshire, Hatfield, UK