| Titre : | Comparing illicit drug use in 19 European cities through sewage analysis (2012) |
| Auteurs : | K. V. THOMAS ; L. BIJLSMA ; S. CASTIGLIONI ; A. COVACI ; E. EMKE ; R. GRABIC ; F. HERNANDEZ ; S. KAROLAK ; B. KASPRZYK-HORDERN ; R. H. LINDBERG ; M. LOPEZ DE ALDA ; A. MEIERJOHANN ; C. ORT ; Y. PICO ; J. B. QUINTANA ; M. REID ; J. RIECKERMANN ; S. TERZIC ; A. L. N. VAN NUIJS ; P. DE VOOGT |
| Type de document : | Article : Périodique |
| Dans : | Science of the Total Environment (Vol.432, 15 August 2012) |
| Article en page(s) : | 432-439 |
| Langues: | Anglais |
| Discipline : | PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods) |
| Mots-clés : |
Thésaurus TOXIBASE COCAINE ; EAUX USEES ; ANALYSE CHIMIQUE ; MESURES QUANTITATIVES ; COMPARAISON ; PRODUIT ILLICITE ; MILIEU URBAIN ; CANNABIS ; ECSTASY ; METHAMPHETAMINE ; AMPHETAMINESThésaurus Géographique BELGIQUE ; ESPAGNE ; FINLANDE ; FRANCE ; ITALIE ; NORVEGE ; PAYS-BAS ; ROYAUME-UNI ; SUEDE ; CROATIE ; REPUBLIQUE TCHEQUE ; EUROPE |
| Résumé : | The analysis of sewage for urinary biomarkers of illicit drugs is a promising and complementary approach for estimating the use of these substances in the general population. For the first time, this approach was simultaneously applied in 19 European cities, making it possible to directly compare illicit drug loads in Europe over a 1-week period. An inter-laboratory comparison study was performed to evaluate the analytical performance of the participating laboratories. Raw 24-hour composite sewage samples were collected from 19 European cities during a single week in March 2011 and analyzed for the urinary biomarkers of cocaine, amphetamine, ecstasy, methamphetamine and cannabis using in-house optimized and validated analytical methods. The load of each substance used in each city was back-calculated from the measured concentrations. The data show distinct temporal and spatial patterns in drug use across Europe. Cocaine use was higher in Western and Central Europe and lower in Northern and Eastern Europe. The extrapolated total daily use of cocaine in Europe during the study period was equivalent to 356 kg/day. High per capita ecstasy loads were observed in Dutch cities, as well as in Antwerp and London. In general, cocaine and ecstasy loads were significantly elevated during the weekend compared to weekdays. Per-capita loads of methamphetamine were highest in Helsinki and Turku, Oslo and Budweis, while the per capita loads of cannabis were similar throughout Europe. This study shows that a standardized analysis for illicit drug urinary biomarkers in sewage can be applied to estimate and compare the use of these substances at local and international scales. This approach has the potential to deliver important information on drug markets (supply indicator). |
| Domaine : | Drogues illicites / Illicit drugs |
| Refs biblio. : | 35 |
| Affiliation : | Norwegian Institute for Water Research (NIVA), Gaustadalleen 21, 0349 Oslo, Norvège |
| Lien : | http://www.sciencedirect.com/science/article/pii/S0048969712008959#FCANote |
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