|Titre :||Lifetime comorbidity of DSM-IV mood and anxiety disorders and specific drug use disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. (2006)|
|Auteurs :||K. P. CONWAY ; W. COMPTON ; F. S. STINSON ; B. F. GRANT|
|Type de document :||Article : Périodique|
|Dans :||Journal of Clinical Psychiatry (Vol.67, n°2, February 2006)|
|Article en page(s) :||247-257|
|Discipline :||PSY (Psychopathologie / Psychopathology)|
Thésaurus TOXIBASECOMORBIDITE ; PREVALENCE ; TROUBLES DE L'HUMEUR ; ANXIETE ; DEPENDANCE ; DSM (III,IV,5) ; PSYCHOTROPES ; PRODUIT ILLICITE
OBJECTIVE: To present nationally representative data on the lifetime prevalence and comorbidity of 8 specific drug use disorders, separately for abuse and dependence, and mood and anxiety disorders.
METHOD: Data come from a representative sample (N=43,093) of the United States civilian, noninstitutional population 18 years and older. Diagnoses of mood, anxiety, and drug use disorders were based upon face-to-face personal interviews using the Alcohol Use Disorder and Associated Disabilities Interview Schedule-DSM-IV Version (AUDADIS-IV).
RESULTS: Associations between specific mood and anxiety disorders and specific drug use disorders were virtually all positive and statistically significant (p<.05 in general associations were greater for dependence than abuse mood anxiety disorders and some instances stronger among women men large odds ratios also observed individuals with comorbid disorders.> CONCLUSION: The comorbidity between specific mood and anxiety disorders and specific drug use disorders is pervasive in the U.S. population. Findings suggest that comorbid psychiatric disorders may increase the risk of greater involvement in more serious illicit drug use disorders and that the greater comorbidity between mood and anxiety and drug use disorders among women may reflect greater deviance and psychopathology among drug-using women than men. Findings also suggest that drug abuse prevention and intervention efforts should address other psychiatric conditions. Further, definitions of drug use disorder phenotypes should give careful consideration to other psychiatric conditions as meaningful characteristics of case heterogeneity.
|Domaine :||Autres substances / Other substances ; Drogues illicites / Illicit drugs|
|Refs biblio. :||35|
|Affiliation :||Division of Epidemiology, Services, and Prevention Research, National Institute on Drug Abuse, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892-9304, USA|