Titre : | Cocaine-related medical and trauma problems: a consecutive series of 743 patients from a multicentre study in Italy (2011) |
Auteurs : | R. M. PAVARIN ; F. LUGOBONI ; S. MATHEWSON ; A. M. FERRARI ; G. GUIZZARDI ; G. QUAGLIO |
Type de document : | Article : Périodique |
Dans : | European Journal of Emergency Medicine (Vol.18, n°4, August 2011) |
Article en page(s) : | 208-214 |
Langues: | Anglais |
Discipline : | PSY (Psychopathologie / Psychopathology) |
Mots-clés : |
Thésaurus géographique ITALIEThésaurus mots-clés COCAINE ; URGENCE ; INTOXICATION ; PSYCHIATRIE ; ETUDE RETROSPECTIVE ; EFFET SECONDAIRE ; SYMPTOME ; PSYCHOPATHOLOGIE ; ANXIETE ; TRAUMATISME ; PATHOLOGIE ORGANIQUE |
Résumé : |
OBJECTIVE: The purpose of this retrospective study was to describe the spectrum of medical and trauma complications associated with self-reported cocaine use.
METHODS: Patient databases of 23 emergency departments were searched for consultations related to cocaine use between January 2007 and December 2008. RESULTS: The population included 569 men (84.4%) and 105 women (15.6%): 505 (74.9%) patients were nondependent cocaine users and 169 (25.1%) were dependent cocaine users. The majority of patients (63.8%) used other drugs in combination with cocaine. Psychiatric symptoms were most frequently reported (60.9%), followed by cardiopulmonary (38.2%), gastrointestinal (22.5%), neurological (20.8%) and constitutional (17.2%) symptoms. Of psychiatric complaints, anxiety was the most common (31.5%). Sex-adjusted and age-adjusted odds ratio (OR) showed that palpitations were associated within 12 h of cocaine use [OR 2.05; 95% confidence interval (CI): 1.12-3.76], and psychotic symptoms (OR 3.05; 95% CI: 1.02-9.18) and hallucinations (OR 7.50; 95% CI: 1.12-50.31) were associated within more than 12 h of the use of cocaine. In a comparison of dependent and nondependent cocaine users, after adjusting for age and sex, cardiopulmonary symptoms (OR 1.56; 95% CI: 1.08-2.24) and paranoia (OR 2.14; 95% CI: 1.08-4.24) were associated with nondependent use of cocaine, and lethargy (OR 7.14; 95% CI: 1.55-35.56) was associated with dependent use of cocaine. The primary cause of trauma was unintentional injuries (32.4%). Sex-adjusted and age-adjusted OR showed a major risk for unintentional injuries with nondependent use of cocaine (OR 6.17; 95% CI: 1.38-42.29). CONCLUSIONS: The study shows that cocaine users experience diverse symptoms and may present with a wide range of physical findings. |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 32 |
Affiliation : | Department of Internal Medicine, Medical Service for Addictive Disorders, University of Verona, Italy |
Cote : | A02693 |
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