Titre : | Cocaine-associated seizures and incidence of status epilepticus (2010) |
Auteurs : | N. MAJLESI ; R. SHIH ; F. W. FIESSELER ; O. HUNG ; R. DEBELLONIO |
Type de document : | Article : Périodique |
Dans : | Western Journal of Emergency Medicine (Vol.11, n°2, May 2010) |
Article en page(s) : | 157-160 |
Langues: | Anglais |
Mots-clés : |
Thésaurus géographique ETATS-UNISThésaurus mots-clés COCAINE ; EPILEPSIE ; ETUDE RETROSPECTIVE ; EFFET SECONDAIRE ; DEPISTAGE |
Mots-clés: | crise |
Résumé : |
OBJECTIVES: Acute complications from cocaine abuse are commonly treated in the emergency department (ED); one of the most consequential is status epilepticus. The incidence of this complication is not clearly defined in the prior literature on cocaine-associated sequelae. We evaluated the incidence of status epilepticus in patients with seizures secondary to suspected cocaine use.
METHODS: We performed a retrospective multi-center study of patients with seizures resulting from cocaine use. We identified study subjects at 15 hospitals by record review and conducted a computer-assisted records search to identify patients with seizures for each institution over a four-year period. We selected subjects from this group on the basis of cocaine use and determined the occurrence of status epilepticus among them. Data were collected on each subject using a standardized data collection form. RESULTS: We evaluated 43 patients in the ED for cocaine-associated seizures. Their age range was 17 to 54, with a mean age was 31 years; 53% were male. Of 43 patients, 42 experienced a single tonic-clonic seizure and one developed status epilepticus. All patients had either a history of cocaine use or positive urine drug screen for cocaine. CONCLUSION: Despite reported cases of status epilepticus with cocaine-induced seizures, the incidence of this complication was unclear based on prior literature. This study shows that most cocaine-associated seizures are self-limited. |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 14 |
Affiliation : | Department of Emergency Medicine, Morristown Memorial Hospital, Morristown, NJ, USA |
Lien : | http://escholarship.org/uc/item/0nm7d20d |
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