Titre : | Dilated cardiomyopathy and cocaine abuse. Report of two cases (1986) |
Auteurs : | R. S. WIENER ; J. T. LOCKHART ; R. G. SCHWARTZ |
Type de document : | Article : Périodique |
Dans : | American Journal of Medicine (Vol.81, n°4, October 1986) |
Article en page(s) : | 699-701 |
Langues: | Anglais |
Discipline : | PAT (Pathologie organique / Organic pathology) |
Mots-clés : |
Thésaurus géographique ETATS-UNISThésaurus mots-clés ETUDE DE CAS ; COCAINE ; COEUR ; PATHOLOGIE ORGANIQUE ; INFARCTUS ; SYMPTOME |
Résumé : | Two young patients with dilated cardiomyopathies associated with long-term use of cocaine are described. A 42-year-old male cocaine abuser with normal coronary arteries experienced recurrent myocardial infarction, with development of a dilated, globally hypocontractile left ventricle. The second patient, a 28-year-old woman with a prominent history of inhaling vaporized cocaine ("free-basing"), presented with symptoms and signs of biventricular heart failure and was found to have a dilated cardiomyopathy. The clinical spectrum of cocaine cardiotoxicity is reviewed, and pathophysiologic mechanisms of cocaine-induced cardiomyopathy are discussed. Long-term cocaine use may cause dilated cardiomyopathy and recurrent myocardial infarction, even in the absence of atherosclerotic epicardial coronary artery disease. |
Domaine : | Drogues illicites / Illicit drugs |
Sous-type de document : | Etude de cas / Case report |
Refs biblio. : | 18 |
Affiliation : | USA |
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