Titre : | A vaccine against cocaine abuse : News and views |
Titre traduit : | (Un vaccin contre l'addiction à la cocaïne) |
Auteurs : | G. SIVAGNANAM |
Type de document : | Périodique |
Année de publication : | 2011 |
ISBN/ISSN/EAN : | 0976-500X |
Format : | 143-144 |
Note générale : | Journal of Pharmacology and Pharmacotherapeutics, April-June 2011, Vol. 2, n°2, p.143-144 |
Langues: | Anglais |
Discipline : | TRA (Traitement et prise en charge / Treatment and care) |
Mots-clés : |
Thésaurus mots-clés COCAINE ; VACCINATION ; MECANISME D'ACTION |
Résumé : | Vaccination promises to be a novel approach, wherein the elicited specific antibodies against a habituating drug (e.g., cocaine) block its access to the brain. The mechanism appears to result from the binding of the drug with the elicited circulating IgG antibodies, making the complex impermeable to the blood-brain barrier so that the drug stays in the periphery, leaving the subject deprived of the "high" (euphoria). [Extract of the document] |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 11 |
Affiliation : |
Indira Gandhi Medical College and Research Institute Kadhirkamam, Puducherry Inde. India. |
Lien : | http://www.jpharmacol.com/text.asp?2011/2/2/143/81921 |
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