Historique
Article de Périodique
Prevalence of drugs of abuse in urine of drivers involved in road accidents in France: a collaborative study (1998)
(Prévalence urinaire de drogues illicites chez des conducteurs impliqués dans un accident de la circulation en France)
Auteur(s) :
MARQUET, P. ;
DELPLA P. A. ;
KERGUELEN S. ;
BREMOND J. ;
FACY, F. ;
GARNIER, M. ;
GUERY B. ;
LHERMITTE, M. ;
MATHE D. ;
PELISSIER, A. L. ;
RENAUDEAU, C. ;
VEST P. ;
SEGUELA J. P.
Année :
1998
Page(s) :
806-811
Langue(s) :
Anglais
Refs biblio. :
21
Domaine :
Drogues illicites / Illicit drugs
Discipline :
EPI (Epidémiologie / Epidemiology)
Thésaurus mots-clés
CONDUITE DE VEHICULE
;
ACCIDENT
;
URINE
;
DEPISTAGE
;
ENQUETE
;
ANALYSE CHIMIQUE
;
PREVALENCE
;
ETUDE RETROSPECTIVE
Thésaurus géographique
FRANCE
Résumé :
The collaborative, anonymous, case-control study was intended to determine the prevalence of opiates, cocaine metabolites, cannabinoids and amphetamines in the urine of drivers injured in road accidents and to compare these values with those of non-accident subjects ("patients") in France. Recruitment was performed nationwide in the emergency departments of five hospitals and comprised 296 "drivers" aged 18 to 35 and 278 non-traumatic "patients" in the same age range. Females represented 28.4% of "drivers" and 44.2% of "patients." Screening for drugs in urine was performed by fluorescence polarization immunoassays in each center. Each positive result was verified using gas chromatography-mass spectrometry (GC-MS), in a single laboratory. Statistical analysis comprised single-step logistic regression and simultaneously took account of confounding factors and the final differences in prevalence values between the two populations or different subgroups. Cannabinoids were found in 13.9% of drivers (16.0% of males and 8.3% of females, p
Affiliation :
Department of Pharmacology-Toxicology and Emergency Care Unit, University Hospital, Limoges, France
Cote :
A00751