Historique
Article de Périodique
There is an alternative Buprenorphine maintenance (2002)
(Il y a une alternative : le traitement de maintenance à la Buprénorphine)
Article en page(s) :
27-30
Refs biblio. :
52
Domaine :
Drogues illicites / Illicit drugs
Langue(s) :
Français
Thésaurus mots-clés
BUPRENORPHINE
;
TRAITEMENT DE MAINTENANCE
;
EVALUATION
;
PRESCRIPTION MEDICALE
;
GROSSESSE
Thésaurus géographique
ETATS-UNIS
Résumé :
ENGLISH :
5 Key practice points from this article. 1/ Clinical observation and controlled clinical trials have established the safety and efficacy of buprenorphine as a an opioid maintenance or, detoxification agent. 2/ Compared to methadone, more patients may drop out especially during induction but after that, given equivalent doses, performance is roughly comparable. 3/ Sublingual tablets with buprenorphine alone, or with the addition of naloxone which appears to reduce abuse potential, have been shown to produce comparable clinical effects to liquid buprenorphine at appropriate doses and to be acceptable to patients. 4/ Dosing strategies ranging from several times a day to two or three times a week appear feasible, reducing both clinic workload and inconvenience for patients without the risk of diversion entailed in take-home doses. 5/ Buprenorphine seems safe in pregnancy and minimises neonatal withdrawal. (Extract of the publication)
ENGLISH :
5 Key practice points from this article. 1/ Clinical observation and controlled clinical trials have established the safety and efficacy of buprenorphine as a an opioid maintenance or, detoxification agent. 2/ Compared to methadone, more patients may drop out especially during induction but after that, given equivalent doses, performance is roughly comparable. 3/ Sublingual tablets with buprenorphine alone, or with the addition of naloxone which appears to reduce abuse potential, have been shown to produce comparable clinical effects to liquid buprenorphine at appropriate doses and to be acceptable to patients. 4/ Dosing strategies ranging from several times a day to two or three times a week appear feasible, reducing both clinic workload and inconvenience for patients without the risk of diversion entailed in take-home doses. 5/ Buprenorphine seems safe in pregnancy and minimises neonatal withdrawal. (Extract of the publication)
Affiliation :
Dpt of Psychiatry and Biobehavioral Sciences, UCLA, 11075 Santa Monica Blvd, Suite 200, Los Angeles, California 90025
Etats-Unis. United States.
Etats-Unis. United States.