Titre : | Short-term memory impairment in cannabis-dependent adolescents |
Titre traduit : | (Troubles de la mémoire de courte durée chez les adolescents dépendants au cannabis) |
Auteurs : | R. H. SCHWARTZ ; P. J. GRUENEWALD ; KLITZNER M. ; FEDIO P. |
Type de document : | Périodique |
Année de publication : | 1989 |
ISBN/ISSN/EAN : | 0002-922X |
Format : | 1214-1219 / graph. ; tabl. |
Note générale : |
American Journal of Diseases of Children, 1989, 143, 1214-1219 |
Langues: | Anglais |
Mots-clés : |
Thésaurus mots-clés CANNABIS ; MEMOIRE ; ADOLESCENT ; TROUBLES DE LA MEMOIRE ; EPIDEMIOLOGIE ; EFFET SECONDAIRE |
Résumé : |
FRANÇAIS : On évalue la mémoire auditive et spatio-visuelle chez dix adolescents toxicomanes au cannabis. On les compare avec un groupe de contrôle comprenant des consommateurs récents de cannabis et neuf adolescents non toxicomanes. On procède à un examen complet avec 7 tests neuropsychologiques avant l'évaluation, puis un autre six semaines après. On trouve une différence significative entre le groupe étudié et les 2 groupes-contrôles. Après six semaines d'abstention de cannabis, le groupe montre une amélioration significative. L'auteur en conclut que l'adolescent cannabis-dépendant a une insuffisance sélective et à court terme à mémoriser, insuffisance qui dure au moins six semaines après les dernières prises de marihuana. ENGLISH : The concentration of delta-9-tetrahydro-cannabinol in marijuana available in the United States has increased by 250% since investigations of the effects of marijuana on short-term memory first appeared in scientific journals. Moreover, previous investigations of short-term memory in long-term marijuana smokers involved adults only. We evaluated the auditory/verbal and visual/spatial memory of 10 cannabis-dependent adolescents and compared the results with performance of 17 subjects in two control groups. The control groups included 8 adolescent drug abusers who had not been long-term users of cannabis and another 9 adolescents who had never abused any drug. All three groups were matched on age, IQ, and absence of previous learning disabilities. Adolescents with a history of frequent alcohol or phencyclidine abuse were excluded from entering the study. A battery of seven neuropsychological tests was administered initially to all subjects and a parallel test battery was administered 6 weeks thereafter. Significant differences between the cannabis-dependent group and the two control groups were obtained initially on the Benton Visual Retention Test (F[2,24] = 6.07) and the Wechsler Memory Scale Prose Passages (F[2,23] = 7.04). After 6 weeks of supervised abstention from intoxicants, subjects in the cannabis-dependent group showed some significant improvement on the Wechsler Memory Prose Passages score and on the Benton Visual Retention Test; however, the improvement failed to achieve statistical significance. We concluded that cannabis-dependent adolescents have selective short-term memory deficits that continue for at least 6 weeks after the last use of marijuana. |
Note de contenu : | graph. ; tabl. |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 24 |
Affiliation : |
Dept Pediat., Georgetown Univ. Sch. Med., Washington DC Etats-Unis. United States. |
Centre Emetteur : | 13 OFDT |
Cote : | A01027 |
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