Titre : | The prevalence and clinical course of sedative-hypnotic abuse and dependence in a large cohort |
Titre traduit : | (Prévalence et caractéristiques cliniques de l'abus et de la dépendance aux hypnotiques sédatifs sur un large échantillon) |
Auteurs : | M. A. SCHUKIT ; T. L. SMITH ; J. KRAMER ; G. DANKO ; F. R. VOLPE |
Type de document : | Périodique |
Année de publication : | 2002 |
Format : | 73-90 / tabl. |
Note générale : |
American Journal of Drug and Alcohol Abuse, 2002, 28, (1), 73-90 |
Langues: | Français |
Discipline : | EPI (Epidémiologie / Epidemiology) |
Mots-clés : |
Thésaurus mots-clés HYPNOTIQUES ; MEDICAMENTS ; BENZODIAZEPINES ; PREVALENCE ; ENQUETE ; ALCOOL ; PRODUIT ILLICITE ; DEPRESSION ; COMORBIDITE ; ABUS |
Résumé : |
ENGLISH : Relatively little is known about the prevalence and clinical characteristics of dependence on sedative-hypnotics, and almost nothing has been published regarding abuse. This report relates information on Diagnostic and Statistical Manual of the American Psychiatric Association (DSM-IIIR) sedative-hypnotic use disorders among subjects from the Collaborative Study on the Genetics of Alcoholism (COGA). A standardized interview was used to generate data on 407 men and women in Group 1 with sedative-hypnotic dependence (4.4% of the COGA sample), 34 in Group 2 with abuse (0.4%), and 3,426 comparison subjects in Group 3 with alcohol dependence in the absence of a sedative-hypnotic use disorder (36.7%). The remaining COGA subjects (48.5 %) were not included as they had neither alcohol nor sedative-hypnotic dependence or abuse. Those with sedative-hypnotic abuse or dependence were more likely to be Caucasian individuals with abuse or dependence on marijuana, cocaine, amphetamines, or opioids. Subjects in Groups 1 and 2 were also more likely to have histories of independent major depressive and panic disorders, as well as substance-induced mood disorders. Those with dependence, compared to abuse, were likely to be women, reported staying intoxicated for a day or more, but noted less abuse of opioids or amphetamines, although Group 2 members also had high rates of difficulties with sedative-hypnotics. These results highlight notable rates of sedative-hypnotic dependence in the COGA families, and indicate that while sedative-hypnotic abuse does occur, and while the clinical course can involve relatively serious problems, it is less common than dependence. (Review' s abstract) |
Note de contenu : | tabl. |
Domaine : | Plusieurs produits / Several products |
Refs biblio. : | 41 |
Affiliation : |
Dpt of Psychiatry (116A), VA San Diego Healthcare System, Univ. of California-San Diego, 3350 La Jolla Village Drive, San Diego, CA 92161-2002 Etats-Unis. United States. |
Numéro Toxibase : | 1300686 |
Centre Emetteur : | 13 OFDT |
Cote : | AJDA |
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