Titre : | Can HIV-1-contaminated syringes be disinfected? Implications for transmission among injection drug users |
Auteurs : | N. ABDALA ; GLEGHORN A. A. ; J. M. CARNEY ; R. HEIMER |
Type de document : | Périodique |
Année de publication : | 2001 |
Format : | 487-494 |
Note générale : |
Journal of Acquired Immune Deficiency Syndromes, 2001, 28, (5), 487-494 |
Langues: | Anglais |
Discipline : | MAL (Maladies infectieuses / Infectious diseases) |
Mots-clés : |
Thésaurus mots-clés VIH ; INJECTION ; SERINGUE ; EAU DE JAVEL ; EFFICACITE ; PREVENTION ; EPIDEMIOLOGIEThésaurus géographique ETATS-UNIS |
Résumé : |
ENGLISH : Bleaching of syringes has been advocated to prevent HIV-1 transmission among injection drug users (IDUs). Bleach is frequently distributed by needle exchange, outreach, and educational programs targeting IDUs. We applied a sensitive HIV-1 microculture assay to determine the effectiveness of bleach in disinfecting syringes contaminated with HIV-1. This study demonstrates that in a laboratory environment designed to replicate injection behaviors, undiluted bleach is highly effective in reducing the viability of HIV-1 even after minimal contact time. However, it did not reduce the HIV-1 recovery to zero. Furthermore, three washes with water were nearly as effective as a single rinse with undiluted bleach in reducing the likelihood that contaminated syringes harbored viable HIV-1. Given the reality that IDUs share syringes and may not have access to a new, sterile syringe for each injection, the results suggest that they should be encouraged through harm reduction interventions to clean their syringes, preferably with undiluted bleach. (Review' s abstract) |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 31 |
Affiliation : |
Dpt of Epidemiology and Public Health, Yale Univ. School of Medicine, New Haven, Connecticut 06520-8034 Etats-Unis. United States. |
Centre Emetteur : | 13 OFDT |
Cote : | A01599 |
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