Historique
Périodique
Buprenorphine in the treatment of opioid dependence
(La buprenorphine dans le traitement de la dépendance aux opioïdes)
Auteur(s) :
E. DAVIDS ;
M. GASTPAR
Article en page(s) :
209-216
Refs biblio. :
101
Domaine :
Drogues illicites / Illicit drugs
Langue(s) :
Français
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus mots-clés
TRAITEMENT DE MAINTENANCE
;
BUPRENORPHINE
;
METHADONE
;
EFFICACITE
;
COMPARAISON
;
SYNDROME DE SEVRAGE
;
EFFET SECONDAIRE
;
GROSSESSE
Note générale :
European Neuropsychopharmacology, 2004, 14, (3), 209-216
Résumé :
ENGLISH :
Buprenorphine has become of increasing interest to be an alternative to methadone in the treatment of heroin addicts. The aim of the paper is to review, from a clinical perspective, the current status of what is known about the pharmacology of buprenorphine, with a particular emphasis on the issues of maintenance therapy in heroin addiction. A systematic review of published follow-up data, from observational and experimental studies was done. Electronic databases Medline and PSYNDEXplus were searched from their earliest entries. Buprenorphine appears to be a well-tolerated drug, with a benign overall side effect. Buprenorphine is an additional treatment option for heroin dependent patients, especially for those who do not wish to start or continue with methadone or for those who do not seem to benefit from adequate dosages of methadone. (Review' s abstract)
ENGLISH :
Buprenorphine has become of increasing interest to be an alternative to methadone in the treatment of heroin addicts. The aim of the paper is to review, from a clinical perspective, the current status of what is known about the pharmacology of buprenorphine, with a particular emphasis on the issues of maintenance therapy in heroin addiction. A systematic review of published follow-up data, from observational and experimental studies was done. Electronic databases Medline and PSYNDEXplus were searched from their earliest entries. Buprenorphine appears to be a well-tolerated drug, with a benign overall side effect. Buprenorphine is an additional treatment option for heroin dependent patients, especially for those who do not wish to start or continue with methadone or for those who do not seem to benefit from adequate dosages of methadone. (Review' s abstract)
Affiliation :
Rhine Clinics Essen, Dpt of Psychiatry and Psychotherapy, Univ. of Duisburg-Essen, Virchowstr. 174, 45147 Essen
Allemagne. Germany.
Allemagne. Germany.
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