Titre : | Long-term outcome of chronic drug use: The Amsterdam Cohort Study among Drug Users (2005) |
Titre traduit : | (Résultats à long terme de l'usage chronique de drogues : étude de la cohorte d'Amsterdam chez les usagers de drogues) |
Auteurs : | TERMORSHUIZEN F. ; KROL A. ; M. PRINS ; E. AMEIJDEN |
Type de document : | Article : Périodique |
Dans : | American Journal of Epidemiology (Vol.161, n°3, February 1, 2005) |
Article en page(s) : | 271-279 |
Langues: | Anglais |
Discipline : | EPI (Epidémiologie / Epidemiology) |
Mots-clés : |
Thésaurus géographique PAYS-BASThésaurus mots-clés DEPENDANCE ; ENQUETE ; HEROINE ; COCAINE ; AMPHETAMINES ; MORTALITE ; PREVALENCE ; TRAJECTOIRE ; ETUDE LONGITUDINALE ; METHADONE ; ABSTINENCE ; MOTIVATION ; REDUCTION DES RISQUES ET DES DOMMAGES ; EPIDEMIOLOGIE ANALYTIQUE ; TYPE D'USAGE |
Résumé : | In the present study, mortality rates and prevalence of abstinence from illicit drugs among persons with a history of addiction to heroin, cocaine, and/or amphetamines were estimated along the drug-using career time scale. Follow-up data on drug use and vital status were analyzed for participants in the Amsterdam Cohort Study among Drug Users (n = 899; 19852002). Participants in the study were primarily recruited at low-threshold methadone outposts. It was estimated that at least 27% of drug users had died within 20 years after starting regular drug use; for half, death had been due to causes unrelated to human immunodeficiency virus. A favorable trend towards abstinence with increasing time since initiation of regular use was observed. However, among those alive, the estimated prevalence of abstinence for at least 4 months from the above drugs and methadone was only 27% at 20 years since initiation. A higher age at initiation, a calendar year of initiation before 1980, and a Western European ethnic origin were associated with higher prevalence of abstinence. These results indicate that the concept of "maturing out" to a drug-free state does not apply to the majority of drug users. Further studies on determinants of individual transitions in drug use are important in order to establish evidence-based intervention strategies. |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 27 |
Affiliation : | Pays-Bas. Netherlands. |
Numéro Toxibase : | 1301079 |
Centre Emetteur : | 13 OFDT |
Lien : | https://doi.org/10.1093/aje/kwi035 |
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