| Titre : | The differential impact of risk factors on illicit drug involvement in females |
| Titre original: | (L'impact différentiel des facteurs de risque d'immersion dans la drogue chez les femmes) |
| Auteurs : | A. AGRAWAL ; C. O. GARDNER ; C. A. PRESCOTT ; K. S. KENDLER |
| Type de document : | Périodique |
| Année de publication : | 2005 |
| Format : | 454-466 |
| Note générale : |
Social Psychiatry and Psychiatric Epidemiology, 2005, 40, (6), 454-466
|
| Langues: | Anglais |
| Discipline : | PSY (Psychopathologie / Psychopathology) |
| Mots-clés : |
Thésaurus TOXIBASE TYPE D'USAGE ; SEXE FEMININ ; FACTEUR DE RISQUE ; PRODUIT ILLICITE ; FRATRIE ; ADULTE ; MILIEU SOCIOCULTUREL ; RELIGION ; STRUCTURE DE LA PERSONNALITE ; ABUS SEXUEL ; PSYCHOPATHOLOGIEThésaurus Géographique ETATS-UNIS |
| Résumé : | Background: Initiation of drug use and progression to abuse/dependence involve complex pathways. Potential risk factors may correlate with initiation or progression or both. Are there risk factors that associate with illicit drug use or illicit drug abuse/dependence? Is the magnitude of the association the same for use and abuse/dependence? Does this pattern of association differ across categories of drugs? Methods: We used data from female-female adult twins to assess the association of 26 putative risk factors with use and abuse/dependence of six illicit psychoactive drugs. Drug involvement was represented by independent dichotomous outcomes and by a single ordinal variable. Odds ratios were obtained by logistic regression and a continuation ratio was used to test the magnitude of association. Results: Factors associate in similar patterns with different drug categories. Some associated factors interact only with initiation while others relate with both stages. There is a stronger association of significant socio-demographic factors with drug use while the psychiatric diagnoses are more strongly associated with progression to abuse/dependence. Conclusions: Risk factors may be use-specific, abuse/dependence-specific or common to use and abuse/dependence. The trend of associations is similar across different illicit drugs. This suggests complex, interacting pathways that determine drug habits in individuals. These results are hypothesis-generating and future studies of causal relationships may draw from the outcomes presented in these analyses. (Author' s abstract) |
| Domaine : | Drogues illicites / Illicit drugs |
| Refs biblio. : | 96 |
| Affiliation : | Washington Univ., School of Medicine, Dept. of Psychiatry, 40 N. Kingshighway, Ste 2, St. Louis (MO) 63108. Etats-Unis. United States. |
| Numéro Toxibase : | 1301209 |
| Centre Emetteur : | 13 OFDT |
| Cote : | A02268 |
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