|Titre :||Development of a rational scale to assess the harm of drugs of potential misuse (2007)|
|Auteurs :||D. NUTT ; L. A. KING ; SAULSBURY W. ; C. BLAKEMORE|
|Type de document :||Article : Périodique|
|Dans :||Lancet (The) (Vol.369, n°9566, Mar 24, 2007)|
|Article en page(s) :||1047-1053|
|Note générale :||
Comment: "Psychoactive drugs of misuse: rationalising the irrational", Hall W., p.972.
"Assessing drug-related harm", Lancet 2007;269(9576):1856-7 & Author's reply.
Comment: Nutt D, 'Government vs science over drug and alcohol policy.', The Lancet 2009;374(9703), p. 1731-1733.
|Discipline :||PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)|
Thésaurus TOXIBASECLASSIFICATION ; PRODUIT ILLICITE ; ECHELLE D'EVALUATION ; PRODUIT LICITE ; DEPENDANCE ; EVALUATION ; VOIE D'ADMINISTRATION ; COMPARAISON ; EFFET SECONDAIRE
|Résumé :||Drug misuse and abuse are major health problems. Harmful drugs are regulated according to classification systems that purport to relate to the harms and risks of each drug. However, the methodology and processes underlying classification systems are generally neither specified nor transparent, which reduces confidence in their accuracy and undermines health education messages. We developed and explored the feasibility of the use of a nine-category matrix of harm, with an expert delphic procedure, to assess the harms of a range of illicit drugs in an evidence-based fashion. We also included five legal drugs of misuse (alcohol, khat, solvents, alkyl nitrites, and tobacco) and one that has since been classified (ketamine) for reference. The process proved practicable, and yielded roughly similar scores and rankings of drug harm when used by two separate groups of experts. The ranking of drugs produced by our assessment of harm differed from those used by current regulatory systems. Our methodology offers a systematic framework and process that could be used by national and international regulatory bodies to assess the harm of current and future drugs of abuse. (Author's abstract)|
|Domaine :||Alcool / Alcohol ; Autres substances / Other substances ; Drogues illicites / Illicit drugs ; Tabac / Tobacco|
|Refs biblio. :||26|
|Affiliation :||Psychopharmacology Unit, University of Bristol, Bristol, UK|
|Centre Emetteur :||13 OFDT|