Titre : | Initiation of benzodiazepines in the elderly after hospitalization (2007) |
Auteurs : | C. M. BELL ; H. D. FISCHER ; S. S. GILL ; B. ZAGORSKI ; SYKORA K. ; WODCHIS W. P. ; HERRMANN N. ; S. E. BRONSKILL ; P. E. LEE ; G. M. ANDERSON ; ROCHON P. A. |
Type de document : | Article : Périodique |
Dans : | Journal of General Internal Medicine (Vol.22, n°7, July 2007) |
Article en page(s) : | 1024-1029 |
Langues: | Anglais |
Discipline : | EPI (Epidémiologie / Epidemiology) |
Mots-clés : |
Thésaurus mots-clés PERSONNE AGEE ; BENZODIAZEPINES ; HOSPITALISATION ; INITIATION ; ETUDE RETROSPECTIVE ; USAGE REGULIERThésaurus géographique CANADA |
Résumé : |
OBJECTIVE: To estimate the rate of new chronic benzodiazepine use after hospitalization in older adults not previously prescribed with benzodiazepines.
DESIGN: Retrospective cohort study using linked, population-based administrative data. SETTING: Ontario, Canada between April 1, 1992 and March 31, 2005. PARTICIPANTS: Community-dwelling seniors who had not been prescribed benzodiazepine drugs in the year before hospitalization were selected from all 1.4 million Ontario residents aged 66 years and older. MAIN OUTCOME MEASURES: New chronic benzodiazepine users, defined as initiation of benzodiazepines within 7 days after hospital discharge and an additional claim within 8 days to 6 months. We used multivariate logistic regression to examine for the effect of hospitalization on the primary outcome after adjusting for confounders. RESULTS: There were 405,128 patient hospitalizations included in the cohort. Benzodiazepines were prescribed to 12,484 (3.1%) patients within 7 days of being discharged from hospital. A total of 6,136 (1.5%) patients were identified as new chronic benzodiazepine users. The rate of new chronic benzodiazepine users decreased over the study period from 1.8% in the first year to 1.2% in the final year (P CONCLUSION: New benzodiazepine prescription after hospitalization occurs frequently in older adults and may result in chronic use. A systemic effort to address this risky practice should be considered. (Author's abstract) |
Domaine : | Autres substances / Other substances |
Refs biblio. : | 42 |
Affiliation : | Department of Medicine, St. Michael's Hospital, 30 Bond Street, Toronto, Ontario, Canada, M5B 1W8, Canada |
Centre Emetteur : | 13 OFDT |
Cote : | A03013 |
Lien : | http://link.springer.com/article/10.1007/s11606-007-0194-4 |
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