|Titre :||A peer-education intervention to reduce injection risk behaviors for HIV and hepatitis C virus infection in young injection drug users|
|Auteurs :||R. S. GARFEIN ; E. T. GOLUB ; A. E. GREENBERG ; H. HAGAN ; D. L. HANSON ; S. M. HUDSON ; F. KAPADIA ; M. H. LATKA ; L. J. OUELLET ; D. W. PURCELL ; S. A. STRATHDEE ; H. THIEDE|
|Type de document :||Périodique|
|Année de publication :||2007|
|Note générale :||
AIDS, 2007, 21, (14), 1923-1932.
Editorial comment: Preventing hepatitis C virus infection in injection drug users: risk reduction is not enough, Page-Shafer K., Hahn J.A., Lum P.J., p. 1967-9.
|Discipline :||MAL (Maladies infectieuses / Infectious diseases)|
Thésaurus TOXIBASEETUDE RANDOMISEE ; INTERVENTION ; INJECTION ; VIH ; HEPATITE ; INFECTION ; ADOLESCENT ; PAIR ; REDUCTION DES RISQUES ET DES DOMMAGES ; JEUNE ADULTE ; EVALUATION
|Résumé :||OBJECTIVES: To evaluate whether a behavioral intervention, which taught peer education skills, could reduce injection and sexual risk behaviors associated with primary HIV and hepatitis C virus infection (HCV) among young injection drug users (IDU). DESIGN: We conducted a randomized controlled trial involving HIV and HCV antibody-negative IDU, aged 15-30 years, recruited in five United States cities. A six-session, small-group, cognitive behavioral, skills-building intervention in which participants were taught peer education skills (n = 431) was compared with a time-equivalent attention control (n = 423). Baseline visits included interviews for sociodemographic, psychosocial, and behavioral factors during the previous 3 months; HIV and HCV antibody testing; and pre/posttest counselling. Procedures were repeated 3 and 6 months postintervention. RESULTS: The intervention produced a 29% greater decline in overall injection risk 6 months postintervention relative to the control [proportional odds ratio 0.71; 95% confidence limit (CL) 0.52, 0.97], and a 76% decrease compared with baseline. Decreases were also observed for sexual risk behaviors, but they did not differ by trial arm. Overall HCV infection incidence (18.4/100 person-years) did not differ significantly across trial arms (relative risk 1.15; 95% CL 0.72, 1.82). No HIV seroconversions were observed. CONCLUSION: Interventions providing information, enhancing risk-reduction skills, and motivating behavior change through peer education training can reduce injection risk behaviors, although risk elimination might be necessary to prevent HCV transmission. (Author' s abstract)|
|Domaine :||Drogues illicites / Illicit drugs|
|Refs biblio. :||56|
|Affiliation :||Division of HIV/AIDS Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA|
|Centre Emetteur :||13 OFDT|