Titre : | Cannabis and alcohol - a close friendship |
Auteurs : | R. MECHOULAM ; L. PARKER |
Type de document : | Périodique |
Année de publication : | 2003 |
Format : | 266-268 |
Note générale : |
Trends in Pharmacological Sciences, 2003, 24, (6), 266-268 |
Langues: | Anglais |
Discipline : | PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods) |
Mots-clés : |
Thésaurus mots-clés ALCOOL ; CANNABIS ; CANNABINOIDES ; MODELE ANIMAL ; NEUROBIOLOGIE ; PHYSIOLOGIE ; RENFORCEMENT |
Résumé : |
ENGLISH : Cannabinoids and alcohol activate the same reward pathways, and the cannabinoid CB(1) receptor system plays an important role in regulating the positive reinforcing properties of alcohol. Indeed, both cannabinoids and alcohol cause the release of dopamine in the nucleus accumbens. Recent research suggests that ethanol preference, which is dependent on CB(1) receptors, is higher in young mice than in old mice, and higher in female mice than in male mice. (Author' s abstract) |
Domaine : | Plusieurs produits / Several products |
Refs biblio. : | 24 |
Affiliation : |
Hebrew University Medical Faculty, Pharmacy School Department of Medicinal Chemistry and Natural Products, Jerusalem 91120. Email : Mechou@cc.huji.ac.il Israël. Israel. |
Centre Emetteur : | 13 OFDT |
Cote : | A03592 |
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