Titre : | Gradual dose taper following chronic buprenorphine |
Titre traduit : | (Diminution graduelles des doses de buprénorphine après un traitement de maintenance.) |
Auteurs : | A. B. BECKER ; E. C. STRAIN ; G. E. BIGELOW ; M. L. STITZER ; R. E. JOHNSON |
Type de document : | Périodique |
Année de publication : | 2001 |
Format : | 111-121 |
Note générale : |
American Journal on Addictions, 2001, 10, (2), 111-121
|
Langues: | Anglais |
Discipline : | TRA (Traitement et prise en charge / Treatment and care) |
Mots-clés : |
Thésaurus mots-clés BUPRENORPHINE ; DESINTOXICATION ; CURE DE DESINTOXICATION ; RECHUTE ; POSOLOGIE |
Résumé : | This paper describes the time course of withdrawal and relapse in opioid-dependent volunteers (n=8) who completed a gradual outpatient buprenorphine dose taper (28 days). Compliance with treatment was very high, as evidenced by clinic attendance (96-100%). Urinalysis showed that 6 of the 8 volunteers had relapsed to opiates by the end of the dose taper, even though reports of withdrawal were generally low. Relapse way have been triggered by a desire to re-experience the drug's positive subjective effects, cravinq, or low motivation to remain drug-free. A longer taper combined with an expanded range of treatments may improve prognosis. (Author' s abstract) |
Domaine : | Autres substances / Other substances |
Affiliation : |
Behavioral Pharmacology Research Unit, Johns Hopkins Bayview Medical Campus, 5510 Nathan Shock Dr., Baltimore, MD 21224. Etats-Unis. United States. |
Numéro Toxibase : | 205605 |
Centre Emetteur : | 02 Coordonnateur |
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