Historique
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Hepatitis C in methadone maintenance patients: prevalence and public policy implications
(L'hépatite C chez les patients en traitement de maintenance à la méthadone : prévalence et implications pour les politiques publiques.)
Auteur(s) :
J. J. McCARTHY ;
N. FLYNN
Article en page(s) :
19-31
Refs biblio. :
33
Domaine :
Drogues illicites / Illicit drugs
Langue(s) :
Anglais
Discipline :
MAL (Maladies infectieuses / Infectious diseases)
Thésaurus mots-clés
HEPATITE
;
INFECTION
;
PREVALENCE
;
EPIDEMIOLOGIE DESCRIPTIVE
;
INJECTION
;
POPULATION A RISQUE
Note générale :
Journal of Addictive Diseases, 2001, 20, (1), 19-31
Note de contenu :
tabl.
Résumé :
ENGLISH :
Objective: This study measured the extent and examined implications of hepatitis C (HCV) infection in a methadone maintenance treatment (MMT) population. Method: Four hundred and sixty patients were tested for HCV-Ab, hepatic enzymes and bilirubin, HCV-RNA, and hepatitis B antibody. Results: Overall, 87% of this population had evidence of HCV-Ab. Among drug injectors (IDU), 96% were HCV-Ab positive. Among a subset of Laotian opium-smoking patients prevalence was only 11%. Sixty-two percent of patients with HCV-Ab had detectable HCV-RNA. Only 41 % had elevated hepatic enzymes, and 5% had elevated bilirubin levels. All age groups were equally infected. Systemic problems in screening and treating HCV in drug users were identified. Conclusion: HCV infection poses significant long-term health risks for this population. Harm reduction interventions aimed at reducing transmission of HCV and other needle-related infectious disease deserves more consideration. (Author' s abstract)
ENGLISH :
Objective: This study measured the extent and examined implications of hepatitis C (HCV) infection in a methadone maintenance treatment (MMT) population. Method: Four hundred and sixty patients were tested for HCV-Ab, hepatic enzymes and bilirubin, HCV-RNA, and hepatitis B antibody. Results: Overall, 87% of this population had evidence of HCV-Ab. Among drug injectors (IDU), 96% were HCV-Ab positive. Among a subset of Laotian opium-smoking patients prevalence was only 11%. Sixty-two percent of patients with HCV-Ab had detectable HCV-RNA. Only 41 % had elevated hepatic enzymes, and 5% had elevated bilirubin levels. All age groups were equally infected. Systemic problems in screening and treating HCV in drug users were identified. Conclusion: HCV infection poses significant long-term health risks for this population. Harm reduction interventions aimed at reducing transmission of HCV and other needle-related infectious disease deserves more consideration. (Author' s abstract)
Affiliation :
2100 Capitol Ave, Sacramento, CA 95816
Etats-Unis. United States.
Etats-Unis. United States.
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