Titre : | Intravenous use of precribed sublingual buprenorphine tablets by drug users receiving maintenance therapy in France |
Titre traduit : | (Usage intraveineux de buprenorphine sublinguale prescrite par les usagers de drogues français substitués) |
Auteurs : | G. VIDAL-TRECAN ; I. VARESCON ; N. NABET ; A. BOISSONNAS |
Type de document : | Périodique |
Année de publication : | 2003 |
Format : | 175-181 / tabl. |
Note générale : |
Drug and Alcohol Dependence, 2003, 69, (2), 175-181 |
Langues: | Anglais |
Discipline : | TRA (Traitement et prise en charge / Treatment and care) |
Mots-clés : |
Thésaurus mots-clés BUPRENORPHINE ; TRAITEMENT DE MAINTENANCE ; PRESCRIPTION MEDICALE ; MESUSAGE ; INJECTIONThésaurus géographique FRANCE |
Résumé : |
ENGLISH : Background. In 1996, sublingual buprenorphine was authorized for prescription in France for maintenance therapy (MT):- MT should facilitate the rehabilitation of opioid-dependent drug users and reduce the risks associated with injection. However, misuse and side effects have been reported. Objectives: To assess the frequency of buprenorphine injection in 404 subjects on buprenorphine MT and to determine the factors associated with the injection of buprenorphine. Methods: A cross-sectional survey was used to collect data from subjects on buprenorphine MT seeking treatment from health care networks, specialized structures, a prison and a hostel in three different regions of France (1998-1999). Information was collected by trained interviewers using a structured questionnaire. Results: About half (46.5%) of the subjects on MT (I88/404) had ever injected buprenorphine; 67.2% of this subgroup had since used both injected and sublingual buprenorphine. Variables associated with buprenorphine injection were having injected a substance other than buprenorphine (odds ratio (OR): 13.18; 95% CI: 5.36=32.42), cannabis use (OR: 2.34; 95% CI: 1.51 -3.63) and having a source of income other than a salary (OR: 1.58; 95% CI: 1.02-2.45) and heroin use (OR: 0.23; 95% CI: 0.09-0.61). Conclusions: To decrease buprenorphine injection, prescribers of buprenorphine should participate in networks with specialized centers, and social and professional rehabilitation programs should be implemented for subjects on buprenorphine MT. (Review's abstract.) |
Note de contenu : | tabl. |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 26 |
Affiliation : |
Dept. Santé Pub. AP-HP CHU Cochin-Port Royal, 24 r. du Faubourg St-Jacques, 75014 Paris France. France. |
Numéro Toxibase : | 804263 |
Centre Emetteur : | 08 CAS Strasbourg |
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