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Périodique
Effects of reducing contingency management values on heroin and cocaine use for buprenorphine- and desipramine-treated patients
(Effets d'une diminution des primes, dans un traitement fondé sur la gestion des contingences, sur la consommation d'héroïne et de cocaïne de patients traités par la buprénorphine et la désipramine.)
Auteur(s) :
T. KOSTEN ;
J. POLING ;
A. OLIVETO
Article en page(s) :
665-671
Refs biblio. :
37
Domaine :
Drogues illicites / Illicit drugs
Langue(s) :
Anglais
Thésaurus mots-clés
HEROINE
;
COCAINE
;
SUBSTITUTION
;
BUPRENORPHINE
;
THERAPIE COMPORTEMENTALE
;
ABSTINENCE
;
EFFICACITE
Note générale :
Addiction, 2003, 98, (5), 665-671
Note de contenu :
graph.
Résumé :
FRANÇAIS :
Les 75 participants de l'étude ont suivi pendant 3 mois un traitement fondé sur la gestion des contingences avec pour chaque test urinaire sans drogue une augmentation de leur prime d'encouragement. Les 3 mois suivants, ils n'ont obtenu une prime que lors de 2, puis de 3 tests consécutifs sans drogue. Cette augmentation des exigences a entraîné une diminution des tests urinaires sans drogue, ce qui suggère la nécessité de plus d'intervention psychologique au cours des traitements de gestion de contingences.
ENGLISH :
Aims: During 3 months where contingency management (CM) had an escalating value for each consecutive drug-free urine (escalating CM), cocaine- and heroin-abusing patients significantly increased drug-free urines. The 'escalating CM' was eliminated during months 4-6 to assess any reduction in drug-free urines. Design: Patients who completed a 3-month, randomized, double-blind, trial evaluating CM versus non-CM and desipramine (DMI) versus placebo, had an 'escalating CM' eliminated during months 4-6. The CM and non-CM groups were compared using thrice-weekly urine samples. Setting: Out-patient buprenorphine maintenance for 6 months. Participants: All 75 of the 160 original study patients who completed month 3 of the clinical trial. Intervention: The `escalating CM' was eliminated for all 3 months and during months 5 and 6 the response requirement was also increased to two and then three consecutive drug-free urines in order to obtain a voucher. Measurements: Urine toxicology for opiates and cocaine. Findings: After eliminating the "escalating CM", the CM group showed a decline in combined opioid- and cocaine-free urines. This decline within the CM group was greater in those treated with DMI than placebo. Conclusions: Buprenorphine with DMI maintained drug abstinence after eliminating the "escalating CM", but not after increasing the response requirement, suggesting the need for more intensive psychosocial interventions during CM. (Author' s abstract)
Les 75 participants de l'étude ont suivi pendant 3 mois un traitement fondé sur la gestion des contingences avec pour chaque test urinaire sans drogue une augmentation de leur prime d'encouragement. Les 3 mois suivants, ils n'ont obtenu une prime que lors de 2, puis de 3 tests consécutifs sans drogue. Cette augmentation des exigences a entraîné une diminution des tests urinaires sans drogue, ce qui suggère la nécessité de plus d'intervention psychologique au cours des traitements de gestion de contingences.
ENGLISH :
Aims: During 3 months where contingency management (CM) had an escalating value for each consecutive drug-free urine (escalating CM), cocaine- and heroin-abusing patients significantly increased drug-free urines. The 'escalating CM' was eliminated during months 4-6 to assess any reduction in drug-free urines. Design: Patients who completed a 3-month, randomized, double-blind, trial evaluating CM versus non-CM and desipramine (DMI) versus placebo, had an 'escalating CM' eliminated during months 4-6. The CM and non-CM groups were compared using thrice-weekly urine samples. Setting: Out-patient buprenorphine maintenance for 6 months. Participants: All 75 of the 160 original study patients who completed month 3 of the clinical trial. Intervention: The `escalating CM' was eliminated for all 3 months and during months 5 and 6 the response requirement was also increased to two and then three consecutive drug-free urines in order to obtain a voucher. Measurements: Urine toxicology for opiates and cocaine. Findings: After eliminating the "escalating CM", the CM group showed a decline in combined opioid- and cocaine-free urines. This decline within the CM group was greater in those treated with DMI than placebo. Conclusions: Buprenorphine with DMI maintained drug abstinence after eliminating the "escalating CM", but not after increasing the response requirement, suggesting the need for more intensive psychosocial interventions during CM. (Author' s abstract)
Affiliation :
VA Connecticut Healthcare System Psychiatry 151D, 950 Campbell Avenue, Bldg 35, West Haven, CT 06516. Email : thomas.kostenyale.edu
Etats-Unis. United States.
Etats-Unis. United States.
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