| Titre : | Is oral fluid analysis as accurate as urinalysis in detecting drug use in a treatment setting ? |
| Titre traduit : | (La détection des drogues dans la salive est-elle aussi précise que la détection urinaire effectuée dans les unités de prise en charge des addictions ?) |
| Auteurs : | G. A. BENNETT ; E. DAVIES ; P. THOMAS |
| Type de document : | Périodique |
| Année de publication : | 2003 |
| Format : | 265-269 / tabl. |
| Note générale : |
Drug and Alcohol Dependence, 2003, 72, (3), 265-269 |
| Langues: | Anglais |
| Discipline : | TRA (Traitement et prise en charge / Treatment and care) |
| Mots-clés : |
Thésaurus mots-clés OPIACES ; SENSIBILITE ; POLYCONSOMMATION ; DEPISTAGE ; TEST ; URINE ; SALIVE ; FIABILITE ; COMPARAISON |
| Résumé : |
ENGLISH : Background: Technology for testing oral fluid (OF) for the presence of drugs is available for treatment services and is more attractive than urinalysis: its validity is not well established. Aims: Compare the accuracy of methods of on-site testing of OF and urine. Design: Comparison of the sensitivity and specificity of on-site testing of samples of OF and urine collected on the same occasion, using subsequent blind laboratory analysis of the same urine samples as the standard. Setting: British addiction treatment service. Participants: 157 drug dependent persons, 89% with evidence of opiates, 73% male, and 85% aged between 20 and 35 years. Measurements: Assessment of presence of four drugs using SYVA ETS urinalysis and Cozart Rapiscan OF Drug Test systems. Laboratory urinalysis using microplate enzyme-immunoassay technique. Results: The sensitivity of OF tests and urinalysis were, respectively, for opiates 91 and 91%, methadone 91 and 94%, and benzodiazepines 6 and 72%. The specificity of OF tests and urinalysis were, respectively, for opiates 78 and 67%, methadone 90 and 95%, and benzodiazepines 95 and 96%. Amphetamine usage was rare. Conclusions: OF testing is as accurate as urinalysis in detecting the presence of opiates and methadone, and the absence of methadone and benzodiazepines. (Review's abstract.) |
| Note de contenu : | tabl. |
| Domaine : | Drogues illicites / Illicit drugs |
| Refs biblio. : | 11 |
| Affiliation : |
Addict. Serv., Dorset Hlth Care NHS Trust, 16-18 Tower Rd., Bournemouth, BH1 4LP Royaume-Uni. United Kingdom. |
| Numéro Toxibase : | 804463 |
| Centre Emetteur : | 08 CAS Strasbourg |
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