| Titre : | Self-reported psychopathological symptoms in recreational ecstasy (MDMA) users are mainly associated with regular cannabis use: further evidence from a combined cross-sectional/longitudinal investigation (2004) |
| Titre traduit : | (Les symptômes psychopathologiques auto-rapportés par les usagers récréatifs d'ecstasy sont souvent associés à un usage régulier de cannabis : recherche de confirmation à partir d'une enquête transversale et longitudinale combinée) |
| Auteurs : | J. DAUMANN ; G. HENSEN ; B. THIMM ; M. REZK ; B. TILL ; E. GOUZOULIS-MAYFRANK |
| Type de document : | Article : Périodique |
| Dans : | Psychopharmacology (Vol.173, n°3-4, May 2004) |
| Article en page(s) : | 398-404 |
| Langues: | Anglais |
| Discipline : | PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods) |
| Mots-clés : |
Thésaurus mots-clés MDMA-ECSTASY ; USAGE RECREATIF ; EFFET SECONDAIRE ; PSYCHOPATHOLOGIE ; AUTOEVALUATION ; CANNABIS ; USAGE REGULIER ; ETUDE TRANSVERSALE ; ETUDE LONGITUDINALE |
| Résumé : | RATIONALE: 3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) has become a widely used recreational drug among young people. This is of great concern, since MDMA is neurotoxic in animal studies and its use has been associated with psychological distress and a variety of self-reported psychiatric symptoms. However, exploring the origins of psychopathology in ecstasy users is hampered by the frequent polydrug use and by the cross-sectional design of all investigations, so far. OBJECTIVES: The present study combines a cross-sectional with a longitudinal approach to further clarify the impact of the use of other illicit drugs on psychopathological symptoms reported by ecstasy users. METHODS: At baseline, we administered self-rating scales for impulsivity, sensation seeking and general psychological complaints to 60 recreational ecstasy users and 30 matched controls. From the initial sample of ecstasy users, 38 subjects were re-examined 18 months later. RESULTS: At baseline, ecstasy users reported significantly more psychological complaints than controls. However, self-reported psychopathology was mainly associated with regular cannabis use. At follow-up, subjects who had abstained from ecstasy use during the follow-up period did not differ from those reporting continued consumption. In contrast, subjects with regular concomitant cannabis use during the follow-up period reported more anxiety, interpersonal sensitivity and obsessive-compulsive behaviour than cannabis-abstinent users. Finally, higher levels of obsessive-compulsive behaviour, interpersonal sensitivity, depression, anxiety, phobic anxiety and paranoid ideation were significantly correlated with the duration of regular interim cannabis use. CONCLUSIONS: The present findings suggest that self-reported psychopathology in ecstasy users is predominantly attributable to concomitant use of cannabis. Abstinence from cannabis and not ecstasy seems to be a reliable predictor for remission of psychological complaints in ecstasy users. (Author' s abstract) |
| Domaine : | Drogues illicites / Illicit drugs |
| Refs biblio. : | 42 |
| Affiliation : |
Dept Psychiatry Psychotherapy, Univ. Cologne, Joseph-Stelzmann-Strasse 9, 50931 Cologne. Allemagne. Germany. |
| Numéro Toxibase : | 207785 |
| Centre Emetteur : | 02 Coordonnateur |
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