Article de Périodique
Self-reported psychopathological symptoms in recreational ecstasy (MDMA) users are mainly associated with regular cannabis use: further evidence from a combined cross-sectional/longitudinal investigation (2004)
(Les symptômes psychopathologiques auto-rapportés par les usagers récréatifs d'ecstasy sont souvent associés à un usage régulier de cannabis : recherche de confirmation à partir d'une enquête transversale et longitudinale combinée)
Auteur(s) :
DAUMANN, J. ;
HENSEN, G. ;
THIMM, B. ;
REZK, M. ;
TILL, B. ;
GOUZOULIS-MAYFRANK, E.
Année :
2004
Page(s) :
398-404
Langue(s) :
Anglais
Refs biblio. :
42
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus mots-clés
MDMA-ECSTASY
;
USAGE RECREATIF
;
EFFET SECONDAIRE
;
PSYCHOPATHOLOGIE
;
AUTOEVALUATION
;
CANNABIS
;
USAGE REGULIER
;
ETUDE TRANSVERSALE
;
ETUDE LONGITUDINALE
Résumé :
RATIONALE: 3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) has become a widely used recreational drug among young people. This is of great concern, since MDMA is neurotoxic in animal studies and its use has been associated with psychological distress and a variety of self-reported psychiatric symptoms. However, exploring the origins of psychopathology in ecstasy users is hampered by the frequent polydrug use and by the cross-sectional design of all investigations, so far. OBJECTIVES: The present study combines a cross-sectional with a longitudinal approach to further clarify the impact of the use of other illicit drugs on psychopathological symptoms reported by ecstasy users. METHODS: At baseline, we administered self-rating scales for impulsivity, sensation seeking and general psychological complaints to 60 recreational ecstasy users and 30 matched controls. From the initial sample of ecstasy users, 38 subjects were re-examined 18 months later. RESULTS: At baseline, ecstasy users reported significantly more psychological complaints than controls. However, self-reported psychopathology was mainly associated with regular cannabis use. At follow-up, subjects who had abstained from ecstasy use during the follow-up period did not differ from those reporting continued consumption. In contrast, subjects with regular concomitant cannabis use during the follow-up period reported more anxiety, interpersonal sensitivity and obsessive-compulsive behaviour than cannabis-abstinent users. Finally, higher levels of obsessive-compulsive behaviour, interpersonal sensitivity, depression, anxiety, phobic anxiety and paranoid ideation were significantly correlated with the duration of regular interim cannabis use. CONCLUSIONS: The present findings suggest that self-reported psychopathology in ecstasy users is predominantly attributable to concomitant use of cannabis. Abstinence from cannabis and not ecstasy seems to be a reliable predictor for remission of psychological complaints in ecstasy users. (Author' s abstract)
Affiliation :
Dept Psychiatry Psychotherapy, Univ. Cologne, Joseph-Stelzmann-Strasse 9, 50931 Cologne.
Allemagne. Germany.
Allemagne. Germany.