Historique
Article de Périodique
Chronic MDMA (ecstasy) use, cognition and mood (2004)
(Usage chronique de MDMA - ecstasy, cognition et humeur)
Auteur(s) :
McCARDLE, K. ;
LUEBBERS, S. ;
CARTER, J. D. ;
CROFT, R. J. ;
STOUGH, C.
Année :
2004
Page(s) :
434-439
Langue(s) :
Anglais
Refs biblio. :
37
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus mots-clés
MDMA-ECSTASY
;
EFFET SECONDAIRE
;
TROUBLES DE L'HUMEUR
;
TROUBLES DE LA MEMOIRE
;
ETUDE TRANSVERSALE
Résumé :
RATIONALE: It has been suggested that 3,4-methylenedioxymethamphetamine (MDMA or ecstasy) causes damage to the serotonergic system, and that this damage results in cognitive and mood impairments. OBJECTIVES: To examine the effect of chronic MDMA usage on a wide battery of cognitive tests and psychological abilities and processes. METHODS: In the present study, the performance of 17 participants with a history of MDMA use was compared to the performance of 15 control subjects on a battery of neuropsychological tests. This battery included tests for depression, immediate word recall, delayed recall, attention and working memory. RESULTS: Results indicated that the MDMA group had significantly higher scores for depression than the control group, and displayed poorer delayed recall and verbal learning than controls after accounting statistically for the effects of cannabis and depression. CONCLUSIONS: These results suggest that MDMA users exhibit difficulties in coding information into long-term memory, display impaired verbal learning, are more easily distracted, and are less efficient at focusing attention on complex tasks. (Author' s abstract)
Affiliation :
Swinburne Centre for Neuropsychology, Swinburne Univ., PO Box 218, 3122 Hawthorn, Victoria.
Australie. Australia.
Australie. Australia.