Titre : | Substance-abusing schizophrenics : do they self-medicate ? |
Titre traduit : | (Les personnes schizophrènes consommant des substances psychoactives pratiquent t'elle l'automédication.) |
Auteurs : | GOSWAMI S. ; S. K. MATTOO ; D. BASU ; G. SINGH |
Type de document : | Périodique |
Année de publication : | 2004 |
Format : | 139-150 / tabl. |
Note générale : |
American Journal on Addictions, 2004, 13, (2), 139-150 |
Langues: | Anglais |
Mots-clés : |
Thésaurus mots-clés COMORBIDITE ; SCHIZOPHRENIE ; AUTOMEDICATION |
Résumé : |
ENGLISH : In spite of having been formulated nearly two decades back, there is as yet no consensus on the validity of the clinically popular self-medication hypothesis (SMH) of substance use disorders in patients with dual diagnosis. SMH broadly proposes that patients use substances in a non-random fashion so that the psychopharmacologic characteristics of particular substances are used to alleviate a variety of psychiatric symptoms and emotional distress. In order to test the SMH empirically, it was broken down to five sub-hypotheses, which were tested in a group of dual-diagnosis schizophrenia (DDS) patients vis-à-vis a group of only-schizophrenia (S) patients (n = 22 each). The DDS group scored lower than the S group regarding general and some specific psychopathology. The DDS patients ascribed reasons for substance use more often for hedonistic pursuit but also for reduction in symptoms and distress. There was a trend for alcohol to be used more for self-medication purposes compared to opioids and cannabis. The perceived effects of these three substances were significantly different on several symptom/distress dimensions. Finally, there was some degree of "match" between symptom-oriented reasons for use of substances and the effect that was perceived. All of this evidence provides a consistent but modest support for the SMH for "some patients, some substances, and some symptoms." The implications are discussed. (Review' s abstract) |
Note de contenu : | tabl. |
Domaine : | Plusieurs produits / Several products |
Refs biblio. : | 30 |
Affiliation : |
Dptmt. Psychiatry, Postgraduate Inst. Méd. Educ. Research, Chandigarh 160012 ; db_smsatyam.net.in Inde. India. |
Numéro Toxibase : | 207473 |
Centre Emetteur : | 02 Coordonnateur |
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