Titre : | Quantitative drug levels in stimulant psychosis: relationship to symptom severity, catecholomines and hyperkinesia |
Titre traduit : | (Evaluation quantitative des taux de drogues dans les psychoses induites par les stimulants : relation avec la gravité des symptômes, les catécholamines et l'hyperkinésie.) |
Auteurs : | S. L. BATKI ; D. S. HARRIS |
Type de document : | Périodique |
Année de publication : | 2004 |
Format : | 461-470 / tabl. |
Note générale : |
American Journal on Addictions, 2004, 13, (5), 461-470 |
Langues: | Anglais |
Discipline : | PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods) |
Mots-clés : |
Thésaurus mots-clés COCAINE ; TROUBLE BIPOLAIRE ; AMPHETAMINES ; PSYCHOSE ; DOSE-REPONSE ; SANG ; URINE ; CATECHOLAMINES |
Résumé : |
ENGLISH : To examine the relationship between quantitative stimulant drug levels, catecholamines, and psychotic symptoms, nineteen patients in a psychiatric emergency service with a diagnosis of amphetamine- or cocaine-induced psychosis were interviewed, and plasma and urine were collected for quantitative assays of stimulant drug and catecholamine metabolite levels. Methamphetamine or amphetamine levels were related to several psychopathology scores and the global hyperkinesia rating. HVA levels were related to global hyperkinesia but not to psychopathology ratings. Although many other factors such as sensitization may play a role, intensity of stimulant-induced psychotic symptoms and stereotypies appears to be at least in part dose-related. (Author' s abstract) |
Note de contenu : | tabl. |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 45 |
Affiliation : |
Dept Psychiatry, Univ. Cincinnati and Cincinnati V.A. Medical Ctr, 3200 Vine St, Cincinnati, OH 45220. E-mail: debra.harrismed.va.gov Etats-Unis. United States. |
Numéro Toxibase : | 207998 |
Centre Emetteur : | 02 Coordonnateur |
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