Historique
Périodique
Buprenorphine versus methadone for opioid dependence : predictor variables for treatment outcome
(Buprénorphine versus méthadone pour le traitement de la dépendance aux opiacés : variables prédictives pour l'évolution du traitement)
Auteur(s) :
GERRA, G. ;
BORELLA F. ;
ZAIMOVIC, A. ;
MOI, G. ;
BUSSANDRI M. ;
BUBICI C. ;
BERTACCA, S.
Année :
2004
Page(s) :
37-45
Langue(s) :
Anglais
Refs biblio. :
40
Domaine :
Drogues illicites / Illicit drugs
Thésaurus mots-clés
BUPRENORPHINE
;
METHADONE
;
OPIACES
;
DEPENDANCE
;
TRAITEMENT DE MAINTENANCE
;
COMPARAISON
;
EFFICACITE
;
RETENTION
Note générale :
Drug and Alcohol Dependence, 2004, 75, (1), 37-45
Note de contenu :
fig. ; graph. ; tabl.
Résumé :
ENGLISH :
The present study compared in a clinical non-experimental setting the efficacy of buprenorphine (BUP) and methadone (METH) in the treatment of opioid dependence: all the subjects included in the study showed severe long-lasting heroin addiction. Participants (154) were applicants to a 12 weeks treatment program, who were assigned to either METH (78) (mean doses 81.5 + 36.4 mg) or BUP (76) (mean doses 9.2 + 3.4 mg) treatment. Aim of the study was to evaluate patient/treatment variables possibly influencing retention rate, abstinence from illicit drugs and mood changes. METH patients showed a higher retention rate at week 4 (78.2 versus 65.8) (P
Affiliation :
Dipto Nazionale Politiche Antidroga, Via Quintino Sella 69, 00187 Roma
Italie. Italy.
Italie. Italy.