Titre : | Reducing diazepam prescribing for illicit drug users: a randomised control study |
Titre traduit : | (Diminution des prescriptions de diazépam chez les usagers de drogues illicites : étude randomisée) |
Auteurs : | L. ELLIOTT ; GLENDAY J. ; L. FREEMAN ; D. AJEDA ; B. JOHNSTON ; M. CHRISTIE ; OGSTON S. |
Type de document : | Périodique |
Année de publication : | 2005 |
Format : | 25-31 / fig. ; tabl. |
Note générale : |
Drug and Alcohol Review, 2005, 24, (1), 25-31 |
Langues: | Anglais |
Discipline : | TRA (Traitement et prise en charge / Treatment and care) |
Mots-clés : |
Thésaurus mots-clés BENZODIAZEPINES ; POLYCONSOMMATION ; MESUSAGE ; PRESCRIPTION MEDICALE ; POSOLOGIE ; COMORBIDITE |
Résumé : |
ENGLISH : Illicit drug users undergoing mandatory reductions in prescribed diazepam were randomly allocated to one of two methods of delivering psychological support to help reduce their prescription: a) an enhanced intervention consisting of skills training and reinforcement, and b) a limited intervention where patients initially received skills training and thereafter only advice. Outcome measures at baseline and six-months consisted of daily diazepam dose, reported illicit drug use, Severity of Dependence Scale, Hospital Anxiety and Depression Scale (HADS), Pittsburgh Sleep Quality Index. Fifty-three of 119 eligible patients agreed to be randomly allocated to the interventions. Those in the enhanced intervention reduced their daily dose of prescribed diazepam from a mean of 27,8 mg to 19,9 mg at six months (5,3 % per month) compared with 29,8 mg to 17,6 mg at six months (7,5 %) among those in the limited intervention group. However, there was no statistically significant difference in the reduction rate between the intervention groups. Approximately 75 % of patients in each group suspended their reduction programme. The enhanced intervention group reported a statistically and clinically greater reduction in the mean HADS depression score (10,6 at baseline and 7,7 at follow-up), compared with a rise from 8,9 to 11,2 in the limited intervention group. In conclusion, it is possible to reduce prescribed diazepam among illicit drug users but not at the rate of 10 % per month set by the study. The difficulties of working with this population necessitate a flexible and possibly long-term approach to reducing prescribed benzodiazepines. (Review's abstract.) |
Note de contenu : | fig. ; tabl. |
Domaine : | Plusieurs produits / Several products |
Refs biblio. : | 26 |
Affiliation : |
Sch. Nursing Midwifery, Univ. Dundee, 11 Airlie Pl., Dundee, DDJ 4HJ.. Email : l.elliottsnm.dundee.uk Royaume-Uni. United Kingdom. |
Numéro Toxibase : | 804901 |
Centre Emetteur : | 08 CAS Strasbourg |
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