Titre : | Reductions in HIV risk behaviors among depressed drug injectors |
Titre traduit : | (Réductions des conduites à risque vis-à-vis du VIH chez des usagers de drogues par injection déprimés.) |
Auteurs : | M. D. STEIN ; B. J. ANDERSON ; SOLOMON D. A. ; B. H. HERMAN ; S. E. RAMSEY ; R. A. BROWN ; I. W. MILLER |
Type de document : | Périodique |
Année de publication : | 2005 |
Format : | 417-432 / tabl. |
Note générale : |
American Journal of Drug and Alcohol Abuse (The), 2005, 31, (3), 417-432 |
Langues: | Anglais |
Discipline : | MAL (Maladies infectieuses / Infectious diseases) |
Mots-clés : |
Thésaurus mots-clés USAGER ; INJECTION ; VIH ; REDUCTION DES RISQUES ET DES DOMMAGES ; DEPRESSION ; PSYCHOTHERAPIE ; ANTIDEPRESSEURS ; EFFICACITE |
Résumé : |
ENGLISH : Objective: To determine if, by reducing depressive symptoms, combined psychotherapy and pharmacotherapy reduces HIV drug risk behavior compared to an assessment-only condition for active drug injectors over 9 months. Design: Randomized controlled trial. Setting: Outpatient academic research office. Patients: Active injection drug users with a DSM-IV diagnosis of major depression, dysthymia, substance-induced mood disorder with depressive features persisting for at least 3 months, or major depression plus dysthymia. In addition, participants had a Hamilton Rating Scale for Depression (MHRSD) score > 13. Intervention: Psychotherapy (8 sessions of cognitive behavioral therapy) plus antidepressant pharmacotherapy over 3 months. Main Outcome Measures: HIV Risk Assessment Battery (RAB) drug scale scores measured at three, six and nine months, and depression remission (MHRSD score = 8). Results: Participants (n = 109) were 64% male, 82% Caucasian, with a mean baseline MHRSD score of 20.7. Depression subtypes included major depression only (63%), substance-induced depression (17%), and double-depression (17%). Overall, study retention at nine months was 89%. Reported HIV drug risk scores decreased sharply over the first 3 months and continued to decline throughout the follow-up period. Between group differences were not significant in the intention-to-treat analysis. However, highly adherent participants had significantly lower HIV drug risk scores at 3 months (p |
Note de contenu : | tabl. |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 26 |
Affiliation : |
Division General Internal Medicine, Rhode Island Hospital, 593 Eddy St., Providence, RI 02903. E-mail: msteinlifespan.org Etats-Unis. United States. |
Numéro Toxibase : | 208542 |
Centre Emetteur : | 02 Coordonnateur |
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