Titre : | Combination treatment for nicotine dependence: state of the science |
Titre traduit : | (Combiner substituts nicotiniques et antidépresseurs ou pharmacothérapie et thérapie comportementale pour le traitement de la dépendance à la nicotine : l'état de la recherche) |
Auteurs : | K. S. INGERSOLL ; J. COHEN |
Type de document : | Périodique |
Année de publication : | 2005 |
Format : | 1923-1943 / tabl. |
Note générale : |
Substance Use and Misuse, 2005, 40, (13-14), 1923-1943 |
Langues: | Anglais |
Discipline : | TRA (Traitement et prise en charge / Treatment and care) |
Mots-clés : |
Thésaurus mots-clés TABAC ; NICOTINE ; DEPENDANCE ; TRAITEMENT ; PHARMACOTHERAPIE ; THERAPIE COMPORTEMENTALE ; ANTIDEPRESSEURS ; SUBSTITUTS NICOTINIQUES |
Résumé : |
ENGLISH : Both nicotine replacement and sustained-release buproprion double the odds of achieving short- and moderate-term abstinence from nicotine. However, questions remain about the efficacy of combining pharmacotherapies. Our purposes were to review the evidence for (1) combined pharmacotherapy and (2) multimodal treatment combining pharmacotherapy and behavioral treatment and to recommend combinations of treatments to reduce nicotine dependence. Combining first-line pharmacotherapies with each other or with investigational drugs shows little benefet. In contrast, trials combining specific behavioral treatments with first-line pharmacotherapies show enhanced smoking cessation rates, but benefits are not seen in all populations. We recommend future directions for research, including better specification of behavioral components and further examination of the length and timing of treatment. (Editor's abstract.) |
Note de contenu : | tabl. |
Domaine : | Tabac / Tobacco / e-cigarette |
Refs biblio. : | 66 |
Affiliation : |
Department of Psychiatry Medicine, University of Virginia, Charlottesville, VA 22908. E-mail : kareningersollgmail.com Etats-Unis. United States. |
Numéro Toxibase : | 405005 |
Centre Emetteur : | 04 CIRDD-51 |
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