Titre : | Self-reported effects of methadone on cigarette smoking in methadone-maintained subjects |
Titre traduit : | (Effets de la méthadone sur la consommation de cigarettes, rapportés par des sujets sous traitement de maintien à la méthadone) |
Auteurs : | H. BARAN-FURGA ; CHMIELEWSKA K. ; BOGUCKA-BONIKOWSKA A. ; HABRAT B. ; KOSTOWSKI W. ; P. BIENKOWSKI |
Type de document : | Périodique |
Année de publication : | 2005 |
Format : | 1103-1111 / tabl. |
Note générale : |
Substance Use and Misuse, 2005, 40, (8), 1103-1111 |
Langues: | Anglais |
Discipline : | PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods) |
Mots-clés : |
Thésaurus mots-clés OPIACES ; DEPENDANCE ; TRAITEMENT DE MAINTENANCE ; SUBSTITUTION ; METHADONE ; TABAC ; CIGARETTE ; NICOTINE ; INTERACTION CHIMIQUE |
Résumé : |
ENGLISH : Subjects maintained on methadone evidence a high level of interest in quitting cigarette smoking. Readiness to quit may result, at least partially, from direct pharmacological interactions between methadone and brain nicotinic acetylcholine receptors. The aim of the present study was to assess: (1) self-reported changes in smoking habits after admission to a methadone maintenance treatment (MMT) program; (2) acute effects of methadone administration on smoking behavior in MMT patients. The study was conducted between May and December 2001, in two public outpatient MMT clinics located in Warsaw, Poland. The patients (41 men, 30 women) reported smoking fewer cigarettes after admission to the program. Most subjects (67.6%) changed their favorite brand of cigarettes after admission. Mean nicotine content (mg/cigarette) significantly decreased. On the other hand, the subjects did not report any effects of methadone administration on smoking parameters. The above findings suggest that initiation of MMT is associated with positive changes in smoking behavior. However, these changes may not be related to direct pharmacological interactions between methadone and nicotine. (Editor's abstract.) |
Note de contenu : | tabl. |
Domaine : | Plusieurs produits / Several products |
Refs biblio. : | 20 |
Affiliation : |
Department of Pharmacology, Institute of Psychiatry and Neurology, 9 Sobieskiego St., PL-02957 Warsaw. E-mail : pbienkoyahoo.com Pologne. Poland. |
Numéro Toxibase : | 404981 |
Centre Emetteur : | 04 CIRDD-51 |
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