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ETUDE RANDOMISEE |
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Article : Périodique
I. SOHI ; K. D. SHIELD ; J. REHM ; M. MONTEIRO |This article updates a 2017 review on the effectiveness of digital interventions for reducing alcohol use in the general population. An updated systematic search of the MEDLINE database was performed in accordance with the Preferred Reporting It[...]Article : Périodique
Does cessation of smoking cause a change in alcohol consumption? Evidence from the Lung Health study
FRANÇAIS : Quoiqu'une relation positive existe entre l'utilisation de cigarettes et la consommation d'alcool, il n'est pas évident si un changement dans l'utilisation de cigarettes est suivi par un changement de la consommation d'alcool. L'étu[...]Article : Périodique
L. AMATO ; S. MINOZZI ; P. P. PANI ; R. SOLIMINI ; S. VECCHI ; P. ZUCCARO ; M. DAVOLI |BACKGROUND: Cocaine dependence is a disorder for which no pharmacological treatment of proven efficacy exists, advances in the neurobiology could guide future medication development. OBJECTIVES: To investigate the efficacy and acceptability of [...]Article : Périodique
G. ADDOLORATO ; L. LEGGIO ; A. FERRULLI ; S. CARDONE ; G. BEDOGNI ; F. CAPUTO ; G. GASBARRINI ; R. LANDOLFI ; Baclofen Study Group |AIMS: To explore the effect of baclofen in a dose of 20 mg three times per day, compared with the already studied dose of 10 mg three times per day, in the treatment of alcohol dependence. METHODS: We present a secondary analysis of a 12-week do[...]Rapport
T. T. MENSINGA ; I. DE VRIES ; M. KRUIDENIER ; C. C. HUNAULT ; I. S. VAN DEN HENGEL-KOOT ; J. W. FIJEN ; M. E. C. LEENDERS ; J. MEULENBELT | Bilthoven : RIVM | 2006Systematic measurements of the concentration of the psycho-active substance delta-9-tetrahydrocannabinol (THC) in 'netherweed' cannabis obtained from coffeeshops in the Netherlands have revealed that the mean THC concentrations have steadily inc[...]Article : Périodique
F. R. LEVIN ; J. J. MARIANI ; D. J. BROOKS ; M. PAVLICOVA ; W. CHENG ; E. V. NUNES |Cannabis dependence is a substantial public health problem. Behavioral treatments have shown promise, but there are no effective medications for cannabis dependence. The purpose of this study was to evaluate the safety and efficacy of dronabinol[...]Périodique
DEHUE T. | 2002ENGLISH : In 1995, the Dutch Minister of Health proposed that a randomized clinical trial (RCT) with heroin-maintenance for severe abusers be conducted. It took nearly four years of lengthy debates before the Dutch Parliament consented to the [...]Article : Périodique
C. DIAZ GOMEZ ; M. NGANTCHA ; N. LE GARJEAN ; N. BROUARD ; M. LASBLEIZ ; M. PERENNES ; F. J. KERDILES ; C. LE LAN ; R. MOIRAND ; A. BELLOU |Background: Introduction to alcohol consumption early in life increases the risk of alcohol dependency and hence motivational interventions are needed in young patients visiting the emergency department (ED). Aim: This study aims to investigate[...]Article : Périodique
S. L. WALSH ; S. D. COMER ; M. R. LOFWALL ; B. VINCE ; N. LEVY-COOPERMAN ; D. KELSH ; M. A. COE ; J. D. JONES ; P. A. NUZZO ; F. TIBERG ; B. SHELDON ; S. KIM |Importance: Buprenorphine is an efficacious, widely used treatment for opioid use disorder (OUD). Daily oral transmucosal formulations can be associated with misuse, diversion, and nonadherence; these limitations may be obviated by a sustained r[...]Article : Périodique
T. R. ARKELL ; F. VINCKENBOSCH ; R. C. KEVIN ; E. L. THEUNISSEN ; I. S. MCGREGOR ; J. G. RAMAEKERS |Question: What is the magnitude and duration of driving impairment following vaporization of cannabis containing varying concentrations of Delta9-tetrahydrocannabinol (THC) and cannabidiol (CBD)? Findings: In this crossover clinical trial that [...]Article : Périodique
TONSTAD S. ; TONNESEN P. ; P. HAJEK ; K. WILLIAMS ; C. BILLING ; K. REEVES ; Varenicline Phase 3 Study Group |FRANÇAIS : Cet essai a pour objectif de déterminer si un traitement de 12 semaines supplémentaires par la varenicline augmente les taux d'abstinence du tabac chez des fumeurs ayant reçu un traitement initial par la varenicline durant 12 semain[...]Article : Périodique
N. BERTHOLET ; E. SCHMUTZ ; J. STUDER ; A. ADAM ; G. GMEL ; J. A. CUNNINGHAM ; J. McNEELY ; J. B. DAEPPEN |Objective: To estimate the effects of providing access to an alcohol intervention based on a smartphone. Design: Randomised controlled trial. Setting: Four higher education institutions in Switzerland. Participants: 1770 students (> =18 yea[...]Article : Périodique
S. HARTLEY ; N. SIMON ; A. LARABI ; I. VAUGIER ; F. BARBOT ; M. A. QUERA-SALVA ; J. C. ALVAREZ |BACKGROUND: The pharmacokinetic-pharmacodynamic relationship between whole blood delta-9-tetrahydrocannabinol (THC) and driving risk is poorly understood. METHODS: Fifteen chronic cannabis consumers (1-2 joints/day; CC) and 15 occasional cannab[...]Article : Périodique
J. M. McQUEEN ; T. E. HOWE ; C. BALLINGER ; J. GODWIN |OBJECTIVE: The purpose of this study was to examine the effectiveness of an alcohol brief intervention (ABI) on alcohol consumption in hazardous or harmful drinkers compared with screening alone within a general hospital setting. METHOD: Follow[...]Article : Périodique
J. LERCH ; S. T. WALTERS ; L. TANG ; F. S. TAXMAN |As many as 80% of the nearly five million adults under community supervision (i.e., probation, parole) are substance involved; however, treatment utilization is low. Using a multi-site randomized controlled trial, we tested the efficacy of in-pe[...]