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ETUDE RANDOMISEE |
Documents disponibles dans cette catégorie (226)
Article : Périodique
P. CAPONNETTO ; D. CAMPAGNA ; F. CIBELLA ; J. B. MORJARIA ; M. CARUSO ; C. RUSSO ; R. POLOSA |Background: Electronic cigarettes (e-cigarettes) are becoming increasingly popular with smokers worldwide. Users report buying them to help quit smoking, to reduce cigarette consumption, to relieve tobacco withdrawal symptoms, and to continue ha[...]Article : Périodique
C. BULLEN ; C. HOWE ; M. LAUGESEN ; H. McROBBIE ; V. PARAG ; J. WILLIMAN ; N. WALKER |BACKGROUND: Electronic cigarettes (e-cigarettes) can deliver nicotine and mitigate tobacco withdrawal and are used by many smokers to assist quit attempts. We investigated whether e-cigarettes are more effective than nicotine patches at helping [...]Article : Périodique
M. S. SOMMERS ; M. S. LYONS ; J. D. FARGO ; B. D. SOMMERS ; C. C. McDONALD ; J. T. SHOPE ; M. F. FLEMING |BACKGROUND: Risky driving and hazardous drinking are associated with significant human and economic costs. Brief interventions for more than one risky behavior have the potential to reduce health-compromising behaviors in populations with multip[...]Article : Périodique
Reinforcement-based interventions are highly efficacious in the treatment of substance use disorders, and their benefits can extend to other areas of functioning as well. In particular, reinforcing participation in job-related activities may be [...]Rapport
P. MICHAUD ; G. DEMORTIERE ; V. KUNZ ; G. LOBBAN ; S. TOUBAL ; V. DORVAULT ; S. LANCRENON ; CARRÉ A. | Nanterre : ANPAA ; BMCM | 2007L'efficacité des interventions brèves a été surtout démontrée en soins primaires. En France, 20 % des adultes n'ont pas vu de médecin généraliste (MG) dans l'année, et la consultation de santé au travail représente la seule occasion d'évaluer la[...]Article : Périodique
O. PHAN ; C. E. HENDERSON ; T. ANGELIDIS ; P. WEIL ; M. VAN TOORN ; R. RIGTER ; C. SORIA ; H. RIGTER |Background: MDFT (Multidimensional Family Therapy) is a family based outpatient treatment programme for adolescent problem behaviour. MDFT has been found effective in the USA in adolescent samples differing in severity and treatment delivery set[...]Article : Périodique
M. P. SCHAUB ; L. J. MAIER ; A. WENGER ; L. STARK ; O. BERG ; T. BECK ; B. B. QUEDNOW ; S. HAUG |BACKGROUND: Web-based self-help interventions that aim to reduce problematic substance use are able to reach "hidden" consumer groups in the general population who often fear stigmatization and thus avoid institutional addiction treatment. In We[...]Article : Périodique
BACKGROUND: Internet-based alcohol misuse prevention programs are now used by many universities. One popular 2- to 3-hour online course known as AlcoholEdu for College is typically required for all incoming freshmen and thus constitutes a campus[...]Article : Périodique
T. D. MARCOTTE ; A. UMLAUF ; D. J. GRELOTTI ; E. G. SONES ; K. F. MASTROPIETRO ; R. T. SUHANDYNATA ; M. A. HUESTIS ; I. GRANT ; R. L. FITZGERALD |Key Points: Question: How accurate are field sobriety tests (FSTs) in identifying acute Delta9-tetrahydrocannabinol (THC) impairment? Findings: In this randomized clinical trial of 184 cannabis users randomized to THC or placebo, law enforceme[...]Article : Périodique
S. W. MILES ; J. SHERIDAN ; B. RUSSELL ; R. KYDD ; A. WHEELER ; C. WALTERS ; G. GAMBLE ; P. HARDLEY ; M. JENSEN ; K. KUOPPASALMI ; P. TUOMOLA ; J. FÖHR ; O. KUIKANMAKI ; H. VORMA ; R. K. SALOKANGAS ; A. MIKKONEN ; M. KALLIO ; J. KAUHANEN ; V. KIVINIEMI ; J. TIIHONEN |Aims To assess the efficacy of methylphenidate as a substitution therapy for amphetamine/methamphetamine dependence in Finland and New Zealand. Design Parallel-group, double-blind, randomized placebo-controlled trial. Setting Out-patient care. P[...]Article : Périodique
G. E. WOODY ; S. A. POOLE ; G. SUBRAMANIAM ; DUGOSH K. ; M. BOGENSCHUTZ ; P. ABBOTT ; A. A. PATKAR ; PUBLICKER M. ; MCCAIN K. ; J. SHARPE POTTER ; R. FORMAN ; VETTER V. ; L. McNICHOLAS ; J. BLAINE ; K. G. LYNCH ; P. J. FUDALA |Context: The usual treatment for opioid-addicted youth is detoxification and counseling. Extended medication-assisted therapy may be more helpful. Objective: To evaluate the efficacy of continuing buprenorphine-naloxone for 12 weeks vs detoxif[...]Article : Périodique
Article : Périodique
AIMS: In order to quantify the effectiveness of family interventions in reducing adolescent drinking, we conducted a meta-analysis of randomized controlled trials. METHODS: We searched the Cochrane Database of Systematic Reviews, ERIC (Educati[...]Article : Périodique
W. N. WELSH ; G. ZAJAC ; K. B. BUCKLEN |Prison-based therapeutic community (TC) drug treatment followed by community aftercare is widely recognized as the most effective treatment paradigm for drug-dependent offenders. However, few randomized experiments have addressed this question a[...]Périodique
T. A. KOSTEN ; GAWIN F. ; T. R. KOSTEN ; B. ROUNSAVILLE | 1993FRANÇAIS : Les connaissances actuelles en matière d'efficacité thérapeutique dans le domaine de la toxicomanie, sont basées sur des expériences auprès de toxicomanes de sexe masculin. Afin de déterminer l'existence éventuelle de différences sel[...]Article : Périodique
G. LO COCO ; F. MELCHIORI ; V. OIENI ; M. R. INFURNA ; B. STRAUSS ; D. SCHWARTZE ; J. ROSENDAHL ; S. GULLO |Background and aims: From residential programs to outpatient services, group therapy permeates the clinical field of substance misuse. While several group interventions for substance use disorders (SUDs) have demonstrated effectiveness, the exis[...]Article : Périodique
AIMS: To test the effectiveness of a digital intervention to reduce cannabis use (ICan) with adherence-focused guidance compared with educational cannabis information. DESIGN: This was a single-blind randomized controlled trial. Follow-up clini[...]Article : Périodique
J. STRANG ; T. GROSHKOVA ; A. UCHTENHAGEN ; W. VAN DEN BRINK ; C. HAASEN ; M. T. SCHECHTER ; N. LINTZERIS ; J. BELL ; A. PIRONA ; E. OVIEDO-JOEKES ; R. SIMON ; N. METREBIAN |BACKGROUND: Supervised injectable heroin (SIH) treatment has emerged over the past 15 years as an intensive treatment for entrenched heroin users who have not responded to standard treatments such as oral methadone maintenance treatment (MMT) or[...]Article : Périodique
S. LOUBIERE ; C. LEMOINE ; M. BOUCEKINE ; L. BOYER ; V. GIRARD ; A. TINLAND ; P. AUQUIER ; FRENCH HOUSING FIRST STUDY GROUP |AIMS: Housing First (HF), a recovery-oriented approach, was proven effective in stabilising housing situations of homeless individuals with severe mental disorders, yet had limited effectiveness on recovery outcomes on a short-term basis compare[...]Article : Périodique
ENGLISH: Background: Adolescent substance use is associated with both earlier childhood behavioural problems and serious lifetime addiction problems later in life. Aims: To examine whether, and through which mechanisms, targeting risk factors [...]Article : Périodique
N. CLARKE ; J. FERRAR ; E. PECHEY ; M. VENTSEL ; M. A. PILLING ; M. R. MUNAFO ; T. M. MARTEAU ; G. J. HOLLANDS |AIMS: To estimate the impact on selection and actual purchasing of (a) health warning labels (text-only and image-and-text) on alcoholic drinks and (b) calorie labels on alcoholic and non-alcoholic drinks. DESIGN: Parallel-groups randomised con[...]Article : Périodique
J. CANTRELL ; D. M. VALLONE ; J. F. THRASHER ; R. H. NAGLER ; S. P. FEIRMAN ; L. R. MUENZ ; D. Y. HE ; K. VISWANATH |Background: The U.S. Family Smoking Prevention and Tobacco Control Act of 2009 requires updating of the existing text-only health warning labels on tobacco packaging with nine new warning statements accompanied by pictorial images. Survey and ex[...]Article : Périodique
C. ROWE ; H. RIGTER ; C. HENDERSON ; A. GANTNER ; K. MOS ; P. NIELSEN ; O. PHAN |Implementation fidelity, a critical aspect of clinical trials research that establishes adequate delivery of the treatment as prescribed in treatment manuals and protocols, is also essential to the successful implementation of effective programs[...]Périodique
W. E. McAULIFFE ; R. S. ASHERY | 1993FRANÇAIS : Cet article met l'accent sur les problèmes de mise en oeuvre des essais "randomisés" de prise en charge psychosociale de toxicomanes en externe. Les auteurs analysent ces problèmes sur neuf études cliniques expérimentales et attiren[...]Article : Périodique
H. RIGTER ; I. PELC ; P. TOSSMANN ; O. PHAN ; E. GRICHTING ; V. HENDRIKS ; C. ROWE |BACKGROUND: In 2003, the governments of Belgium, France, Germany, the Netherlands and Switzerland agreed that there was a need in Europe for a treatment programme for adolescents with cannabis use disorders and other behavioural problems. Based [...]Article : Périodique
G. J. BOTVIN ; K. W. GRIFFIN ; C. BOTVIN ; M. MURPHY ; B. ACEVEDO |Objective: A substantial barrier to translating prevention science into practice is the potential for low implementation fidelity when evidence-based interventions are delivered in real-world settings. This study tested the extent to which enhan[...]Article : Périodique
C. M. LEE ; J. R. KILMER ; C. NEIGHBORS ; D. C. ATKINS ; C. ZHENG ; D. D. WALKER ; M. E. LARIMER |Objective: Marijuana is the most frequently reported illicit substance used on college campuses. Despite the prevalence, few published intervention studies have focused specifically on addressing high-risk marijuana use on college campuses. The [...]Article : Périodique
BACKGROUND Opioid dependence is associated with low rates of treatment-seeking, poor adherence to treatment, frequent relapse, and major societal consequences. We aimed to assess the efficacy, safety, and patient-reported outcomes of an injectab[...]Article : Périodique
N. BERTHOLET ; J. A. CUNNINGHAM ; M. FAOUZI ; J. GAUME ; G. GMEL ; B. BURNAND ; J. B. DAEPPEN |Aim: To test the efficacy of an internet-based brief intervention (IBI) in decreasing alcohol use among young Swiss men aged 21 years on average. Design: Two parallel-group randomized controlled trial with a 1 : 1 allocation ratio containing fo[...]Article : Périodique
M. JOHANSSON ; K. SINADINOVIC ; M. GAJECKI ; P. LINDNER ; A. H. BERMAN ; U. HERMANSSON ; S. ANDREASSON |BACKGROUND AND AIMS: Most people with alcohol use disorder (AUD) are never treated. Internet-based interventions are effective in reducing alcohol consumption and could help to overcome some of the barriers to people not seeking or receiving tre[...]Article : Périodique
C. BOURDUGE ; G. BROUSSE ; F. MOREL ; B. PEREIRA ; C. LAMBERT ; M. IZAUTE ; F. TEISSEDRE |The "Intervention Program based on Self" (IPSELF) project was created to address the gap between the acquisition of life skills during prevention programs and their application with a session for developing one's self-concept included in the Eur[...]Article : Périodique
P. MICHAUD ; V. KUNZ ; G. DEMORTIERE ; CARRÉ A. ; S. LANCRENON ; C. MENARD |Les interventions brèves (IB) sont très efficaces pour diminuer le fardeau sanitaire lié à l'alcool, mais aucune étude n'a évalué jusqu'à ce jour leur efficacité en santé au travail. EIST est une étude randomisée contrôlée réalisée auprès de sal[...]Article : Périodique
Background: This is an updated version of a Cochrane review first published in Issue 3, 2006 (Perry 2006). The review represents one in a family of four reviews focusing on the effectiveness of interventions in reducing drug use and criminal act[...]Article : Périodique
We aimed to determine the relative effectiveness of an education intervention and a threat-of-enforcement intervention in reducing sales of cigarettes to under-age youth by randomly allocating 300 retailers in a nonmetropolitan region of New Sou[...]Livre
Evidence from randomized controlled clinical trials is widely accepted as the only sound basis for assessing the efficacy of new medical treatments. Statistical methods play a key role in all stages of these trials, including their justification[...]Article : Périodique
Aims: To assess the effect of a tailored multi-faceted improvement programme on general practitioners' (GPs') behaviour towards prevention of hazardous and harmful alcohol consumption. The improvement programme consisted of activities aimed at t[...]Article : Périodique
J. GAUME ; G. GMEL ; M. FAOUZI ; N. BERTHOLET ; J. B. DAEPPEN |BACKGROUND: Heavy drinking is one of the leading causes of morbidity and mortality in young men. Brief motivational intervention (BMI) has shown promising results for young people, but has never been tested in young men in the community who volu[...]Article : Périodique
C. HAASEN ; U. VERTHEIN ; F. J. EIROA-OROSA ; I. SCHAFER ; J. REIMER |BACKGROUND/AIMS: Until now, the medical prescription of diamorphine (heroin) has been suggested as suitable for patients who have failed previous maintenance treatments. The aim of this paper is to assess the effects of diamorphine on opioid-dep[...]Thèse, mémoire
J. CAILLON, Auteur ; L. ROMO, Directeur de thèse ; M. GRALL-BRONNEC, Directeur de thèse | 2018FRANÇAIS : Les jeux de hasard et d'argent sur Internet présentent des caractéristiques addictogènes particulièrement à risque de perte de contrôle. Ainsi, en 2017, 13% des joueurs français sur Internet étaient considérés comme des joueurs exces[...]Article : Périodique
M. LAGADEC ; M. REYNAUD ; A. AMIROUCHE ; A. LUQUIENS |FRANÇAIS : Le jeu en ligne problématique et pathologique est devenu un challenge de santé publique du fait de sa prévalence croissante et du peu de recours aux soins des sujets affectés. L'essai thérapeutique randomisé en ligne est une concepti[...]Article : Périodique
INTRODUCTION: There is a noticeable increase in hazardous alcohol use during adolescence, which is significantly associated with adverse consequences. In Germany, up to 30% of adolescents report regular heavy episodic drinking. However, only a f[...]Article : Périodique
D. H. GEMSON ; H. L. MOATS ; B. X. WATKINS ; M. L. GANZ ; S. ROBINSON ; E. HEALTON |OBJECTIVES: This study compared the impact of educational and enforcement interventions on retailers' sale of tobacco to minors in Central Harlem, New York. METHODS: In a randomized trial with repeated measures, 152 stores were randomly divide[...]Article : Périodique
Objective: To examine the long-term effects of a personality-targeted intervention on drinking quantity and frequency (QF), problem drinking, and personality-specific motivations for alcohol use in early adolescence. Method: A randomized contr[...]Article : Périodique
PURPOSE: This randomized clinical trial examined longitudinal outcomes from an alcohol abuse prevention program aimed at urban youths. METHODS: Study participants were an ethnically and racially heterogeneous sample of early adolescents, recru[...]Article : Périodique
J. LE HOUEZEC ; R. HALLIDAY ; N. L. BENOWITZ ; E. CALLAWAY ; H. NAYLOR ; K. HERZIG |Many studies have found that cigarette smoking or nicotine improves mental functioning in abstinent smokers. An unresolved issue is whether this improvement is due primarily to a direct facilitation of performance or to relief of the impairment [...]Article : Périodique
Magnesium in the treatment of alcohol withdrawal syndrome: a multicenter randomized controlled trial
G. AIRAGNES ; R. VALTER ; G. DUCOUTUMANY ; C. VANSTEENE ; J. B. TRABUT ; P. GORWOOD ; C. DUBERTRET ; J. MATTA ; A. CHARLES-NELSON ; F. LIMOSIN |OBJECTIVE: Alcohol withdrawal syndrome (AWS) is a frequent and potentially life-threatening condition experienced in alcohol use disorder. Since hypomagnesemia is involved in AWS's severity, we conducted a multicenter double-blind randomized pla[...]Périodique
R. S. SCHOTTENFELD ; M. C. CHAWARSKI ; MAZLAN M. | 2008ENGLISH : BACKGROUND: Expansion of access to effective treatments for heroin dependence is a worldwide health priority that will also reduce HIV transmission. We compared the efficacy of naltrexone, buprenorphine, and no additional treatment, [...]Article : Périodique
S. LARNEY ; H. JONES ; T. RHODES ; M. HICKMAN |Epidemiology is a core discipline generating evidence to inform and drive drug policy. In this essay, we speculate on what the future of drug epidemiology might become. We highlight for attention two areas shaping the future of drug epidemiology[...]Article : Périodique
Background: Marijuana use is common among U.S. college students. Liberalization of marijuana use policies is hypothesized to decrease social norms discouraging use, which protects against marijuana use. This may increase the importance of protec[...]Bulletin : Périodique
Addiction, Vol.107, Suppl.1 - November 2012 - Maternal Opioid Treatment: Human Experimental Research (MOTHER) Study
E. S. BANDSTRA, Éditeur scientifique | 2012CONTENTS: • Maternal Opioid Treatment: Human Experimental Research (MOTHER) Study: maternal, fetal and neonatal outcomes from secondary analyses. Bandstra E.S., p. 1-4. • Buprenorphine treatment of opioid-dependent pregnant women: a comprehens[...]