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ETUDE RANDOMISEE |
Documents disponibles dans cette catégorie (227)
Article : Périodique
C. BULLEN ; C. HOWE ; M. LAUGESEN ; H. McROBBIE ; V. PARAG ; J. WILLIMAN ; N. WALKER |BACKGROUND: Electronic cigarettes (e-cigarettes) can deliver nicotine and mitigate tobacco withdrawal and are used by many smokers to assist quit attempts. We investigated whether e-cigarettes are more effective than nicotine patches at helping [...]Article : Périodique
M. S. SOMMERS ; M. S. LYONS ; J. D. FARGO ; B. D. SOMMERS ; C. C. McDONALD ; J. T. SHOPE ; M. F. FLEMING |BACKGROUND: Risky driving and hazardous drinking are associated with significant human and economic costs. Brief interventions for more than one risky behavior have the potential to reduce health-compromising behaviors in populations with multip[...]Article : Périodique
Reinforcement-based interventions are highly efficacious in the treatment of substance use disorders, and their benefits can extend to other areas of functioning as well. In particular, reinforcing participation in job-related activities may be [...]Rapport
P. MICHAUD ; G. DEMORTIERE ; V. KUNZ ; G. LOBBAN ; S. TOUBAL ; V. DORVAULT ; S. LANCRENON ; CARRÉ A. | Nanterre : ANPAA ; BMCM | 2007L'efficacité des interventions brèves a été surtout démontrée en soins primaires. En France, 20 % des adultes n'ont pas vu de médecin généraliste (MG) dans l'année, et la consultation de santé au travail représente la seule occasion d'évaluer la[...]Article : Périodique
O. PHAN ; C. E. HENDERSON ; T. ANGELIDIS ; P. WEIL ; M. VAN TOORN ; R. RIGTER ; C. SORIA ; H. RIGTER |Background: MDFT (Multidimensional Family Therapy) is a family based outpatient treatment programme for adolescent problem behaviour. MDFT has been found effective in the USA in adolescent samples differing in severity and treatment delivery set[...]Article : Périodique
M. P. SCHAUB ; L. J. MAIER ; A. WENGER ; L. STARK ; O. BERG ; T. BECK ; B. B. QUEDNOW ; S. HAUG |BACKGROUND: Web-based self-help interventions that aim to reduce problematic substance use are able to reach "hidden" consumer groups in the general population who often fear stigmatization and thus avoid institutional addiction treatment. In We[...]Article : Périodique
BACKGROUND: Internet-based alcohol misuse prevention programs are now used by many universities. One popular 2- to 3-hour online course known as AlcoholEdu for College is typically required for all incoming freshmen and thus constitutes a campus[...]Article : Périodique
T. D. MARCOTTE ; A. UMLAUF ; D. J. GRELOTTI ; E. G. SONES ; K. F. MASTROPIETRO ; R. T. SUHANDYNATA ; M. A. HUESTIS ; I. GRANT ; R. L. FITZGERALD |Key Points: Question: How accurate are field sobriety tests (FSTs) in identifying acute Delta9-tetrahydrocannabinol (THC) impairment? Findings: In this randomized clinical trial of 184 cannabis users randomized to THC or placebo, law enforceme[...]Article : Périodique
S. W. MILES ; J. SHERIDAN ; B. RUSSELL ; R. KYDD ; A. WHEELER ; C. WALTERS ; G. GAMBLE ; P. HARDLEY ; M. JENSEN ; K. KUOPPASALMI ; P. TUOMOLA ; J. FÖHR ; O. KUIKANMAKI ; H. VORMA ; R. K. SALOKANGAS ; A. MIKKONEN ; M. KALLIO ; J. KAUHANEN ; V. KIVINIEMI ; J. TIIHONEN |Aims To assess the efficacy of methylphenidate as a substitution therapy for amphetamine/methamphetamine dependence in Finland and New Zealand. Design Parallel-group, double-blind, randomized placebo-controlled trial. Setting Out-patient care. P[...]Article : Périodique
G. E. WOODY ; S. A. POOLE ; G. SUBRAMANIAM ; DUGOSH K. ; M. BOGENSCHUTZ ; P. ABBOTT ; A. A. PATKAR ; PUBLICKER M. ; MCCAIN K. ; J. SHARPE POTTER ; R. FORMAN ; VETTER V. ; L. McNICHOLAS ; J. BLAINE ; K. G. LYNCH ; P. J. FUDALA |Context: The usual treatment for opioid-addicted youth is detoxification and counseling. Extended medication-assisted therapy may be more helpful. Objective: To evaluate the efficacy of continuing buprenorphine-naloxone for 12 weeks vs detoxif[...]Article : Périodique
Article : Périodique
AIMS: In order to quantify the effectiveness of family interventions in reducing adolescent drinking, we conducted a meta-analysis of randomized controlled trials. METHODS: We searched the Cochrane Database of Systematic Reviews, ERIC (Educati[...]Article : Périodique
W. N. WELSH ; G. ZAJAC ; K. B. BUCKLEN |Prison-based therapeutic community (TC) drug treatment followed by community aftercare is widely recognized as the most effective treatment paradigm for drug-dependent offenders. However, few randomized experiments have addressed this question a[...]Périodique
T. A. KOSTEN ; GAWIN F. ; T. R. KOSTEN ; B. ROUNSAVILLE | 1993FRANÇAIS : Les connaissances actuelles en matière d'efficacité thérapeutique dans le domaine de la toxicomanie, sont basées sur des expériences auprès de toxicomanes de sexe masculin. Afin de déterminer l'existence éventuelle de différences sel[...]Article : Périodique
G. LO COCO ; F. MELCHIORI ; V. OIENI ; M. R. INFURNA ; B. STRAUSS ; D. SCHWARTZE ; J. ROSENDAHL ; S. GULLO |Background and aims: From residential programs to outpatient services, group therapy permeates the clinical field of substance misuse. While several group interventions for substance use disorders (SUDs) have demonstrated effectiveness, the exis[...]Article : Périodique
AIMS: To test the effectiveness of a digital intervention to reduce cannabis use (ICan) with adherence-focused guidance compared with educational cannabis information. DESIGN: This was a single-blind randomized controlled trial. Follow-up clini[...]Article : Périodique
J. STRANG ; T. GROSHKOVA ; A. UCHTENHAGEN ; W. VAN DEN BRINK ; C. HAASEN ; M. T. SCHECHTER ; N. LINTZERIS ; J. BELL ; A. PIRONA ; E. OVIEDO-JOEKES ; R. SIMON ; N. METREBIAN |BACKGROUND: Supervised injectable heroin (SIH) treatment has emerged over the past 15 years as an intensive treatment for entrenched heroin users who have not responded to standard treatments such as oral methadone maintenance treatment (MMT) or[...]Article : Périodique
S. LOUBIERE ; C. LEMOINE ; M. BOUCEKINE ; L. BOYER ; V. GIRARD ; A. TINLAND ; P. AUQUIER ; FRENCH HOUSING FIRST STUDY GROUP |AIMS: Housing First (HF), a recovery-oriented approach, was proven effective in stabilising housing situations of homeless individuals with severe mental disorders, yet had limited effectiveness on recovery outcomes on a short-term basis compare[...]Article : Périodique
ENGLISH: Background: Adolescent substance use is associated with both earlier childhood behavioural problems and serious lifetime addiction problems later in life. Aims: To examine whether, and through which mechanisms, targeting risk factors [...]Article : Périodique
N. CLARKE ; J. FERRAR ; E. PECHEY ; M. VENTSEL ; M. A. PILLING ; M. R. MUNAFO ; T. M. MARTEAU ; G. J. HOLLANDS |AIMS: To estimate the impact on selection and actual purchasing of (a) health warning labels (text-only and image-and-text) on alcoholic drinks and (b) calorie labels on alcoholic and non-alcoholic drinks. DESIGN: Parallel-groups randomised con[...]Article : Périodique
J. CANTRELL ; D. M. VALLONE ; J. F. THRASHER ; R. H. NAGLER ; S. P. FEIRMAN ; L. R. MUENZ ; D. Y. HE ; K. VISWANATH |Background: The U.S. Family Smoking Prevention and Tobacco Control Act of 2009 requires updating of the existing text-only health warning labels on tobacco packaging with nine new warning statements accompanied by pictorial images. Survey and ex[...]Article : Périodique
C. ROWE ; H. RIGTER ; C. HENDERSON ; A. GANTNER ; K. MOS ; P. NIELSEN ; O. PHAN |Implementation fidelity, a critical aspect of clinical trials research that establishes adequate delivery of the treatment as prescribed in treatment manuals and protocols, is also essential to the successful implementation of effective programs[...]Périodique
W. E. McAULIFFE ; R. S. ASHERY | 1993FRANÇAIS : Cet article met l'accent sur les problèmes de mise en oeuvre des essais "randomisés" de prise en charge psychosociale de toxicomanes en externe. Les auteurs analysent ces problèmes sur neuf études cliniques expérimentales et attiren[...]Article : Périodique
H. RIGTER ; I. PELC ; P. TOSSMANN ; O. PHAN ; E. GRICHTING ; V. HENDRIKS ; C. ROWE |BACKGROUND: In 2003, the governments of Belgium, France, Germany, the Netherlands and Switzerland agreed that there was a need in Europe for a treatment programme for adolescents with cannabis use disorders and other behavioural problems. Based [...]Article : Périodique
G. J. BOTVIN ; K. W. GRIFFIN ; C. BOTVIN ; M. MURPHY ; B. ACEVEDO |Objective: A substantial barrier to translating prevention science into practice is the potential for low implementation fidelity when evidence-based interventions are delivered in real-world settings. This study tested the extent to which enhan[...]Article : Périodique
C. M. LEE ; J. R. KILMER ; C. NEIGHBORS ; D. C. ATKINS ; C. ZHENG ; D. D. WALKER ; M. E. LARIMER |Objective: Marijuana is the most frequently reported illicit substance used on college campuses. Despite the prevalence, few published intervention studies have focused specifically on addressing high-risk marijuana use on college campuses. The [...]Article : Périodique
BACKGROUND Opioid dependence is associated with low rates of treatment-seeking, poor adherence to treatment, frequent relapse, and major societal consequences. We aimed to assess the efficacy, safety, and patient-reported outcomes of an injectab[...]Article : Périodique
N. BERTHOLET ; J. A. CUNNINGHAM ; M. FAOUZI ; J. GAUME ; G. GMEL ; B. BURNAND ; J. B. DAEPPEN |Aim: To test the efficacy of an internet-based brief intervention (IBI) in decreasing alcohol use among young Swiss men aged 21 years on average. Design: Two parallel-group randomized controlled trial with a 1 : 1 allocation ratio containing fo[...]Article : Périodique
M. JOHANSSON ; K. SINADINOVIC ; M. GAJECKI ; P. LINDNER ; A. H. BERMAN ; U. HERMANSSON ; S. ANDREASSON |BACKGROUND AND AIMS: Most people with alcohol use disorder (AUD) are never treated. Internet-based interventions are effective in reducing alcohol consumption and could help to overcome some of the barriers to people not seeking or receiving tre[...]Article : Périodique
C. BOURDUGE ; G. BROUSSE ; F. MOREL ; B. PEREIRA ; C. LAMBERT ; M. IZAUTE ; F. TEISSEDRE |The "Intervention Program based on Self" (IPSELF) project was created to address the gap between the acquisition of life skills during prevention programs and their application with a session for developing one's self-concept included in the Eur[...]Article : Périodique
P. MICHAUD ; V. KUNZ ; G. DEMORTIERE ; CARRÉ A. ; S. LANCRENON ; C. MENARD |Les interventions brèves (IB) sont très efficaces pour diminuer le fardeau sanitaire lié à l'alcool, mais aucune étude n'a évalué jusqu'à ce jour leur efficacité en santé au travail. EIST est une étude randomisée contrôlée réalisée auprès de sal[...]Article : Périodique
Background: This is an updated version of a Cochrane review first published in Issue 3, 2006 (Perry 2006). The review represents one in a family of four reviews focusing on the effectiveness of interventions in reducing drug use and criminal act[...]Article : Périodique
We aimed to determine the relative effectiveness of an education intervention and a threat-of-enforcement intervention in reducing sales of cigarettes to under-age youth by randomly allocating 300 retailers in a nonmetropolitan region of New Sou[...]Livre
Evidence from randomized controlled clinical trials is widely accepted as the only sound basis for assessing the efficacy of new medical treatments. Statistical methods play a key role in all stages of these trials, including their justification[...]Article : Périodique
Aims: To assess the effect of a tailored multi-faceted improvement programme on general practitioners' (GPs') behaviour towards prevention of hazardous and harmful alcohol consumption. The improvement programme consisted of activities aimed at t[...]Article : Périodique
J. GAUME ; G. GMEL ; M. FAOUZI ; N. BERTHOLET ; J. B. DAEPPEN |BACKGROUND: Heavy drinking is one of the leading causes of morbidity and mortality in young men. Brief motivational intervention (BMI) has shown promising results for young people, but has never been tested in young men in the community who volu[...]Article : Périodique
C. HAASEN ; U. VERTHEIN ; F. J. EIROA-OROSA ; I. SCHAFER ; J. REIMER |BACKGROUND/AIMS: Until now, the medical prescription of diamorphine (heroin) has been suggested as suitable for patients who have failed previous maintenance treatments. The aim of this paper is to assess the effects of diamorphine on opioid-dep[...]Thèse, mémoire
J. CAILLON, Auteur ; L. ROMO, Directeur de thèse ; M. GRALL-BRONNEC, Directeur de thèse | 2018FRANÇAIS : Les jeux de hasard et d'argent sur Internet présentent des caractéristiques addictogènes particulièrement à risque de perte de contrôle. Ainsi, en 2017, 13% des joueurs français sur Internet étaient considérés comme des joueurs exces[...]Article : Périodique
M. LAGADEC ; M. REYNAUD ; A. AMIROUCHE ; A. LUQUIENS |FRANÇAIS : Le jeu en ligne problématique et pathologique est devenu un challenge de santé publique du fait de sa prévalence croissante et du peu de recours aux soins des sujets affectés. L'essai thérapeutique randomisé en ligne est une concepti[...]Article : Périodique
INTRODUCTION: There is a noticeable increase in hazardous alcohol use during adolescence, which is significantly associated with adverse consequences. In Germany, up to 30% of adolescents report regular heavy episodic drinking. However, only a f[...]Article : Périodique
D. H. GEMSON ; H. L. MOATS ; B. X. WATKINS ; M. L. GANZ ; S. ROBINSON ; E. HEALTON |OBJECTIVES: This study compared the impact of educational and enforcement interventions on retailers' sale of tobacco to minors in Central Harlem, New York. METHODS: In a randomized trial with repeated measures, 152 stores were randomly divide[...]Article : Périodique
Objective: To examine the long-term effects of a personality-targeted intervention on drinking quantity and frequency (QF), problem drinking, and personality-specific motivations for alcohol use in early adolescence. Method: A randomized contr[...]Article : Périodique
PURPOSE: This randomized clinical trial examined longitudinal outcomes from an alcohol abuse prevention program aimed at urban youths. METHODS: Study participants were an ethnically and racially heterogeneous sample of early adolescents, recru[...]Article : Périodique
J. LE HOUEZEC ; R. HALLIDAY ; N. L. BENOWITZ ; E. CALLAWAY ; H. NAYLOR ; K. HERZIG |Many studies have found that cigarette smoking or nicotine improves mental functioning in abstinent smokers. An unresolved issue is whether this improvement is due primarily to a direct facilitation of performance or to relief of the impairment [...]Article : Périodique
Magnesium in the treatment of alcohol withdrawal syndrome: a multicenter randomized controlled trial
G. AIRAGNES ; R. VALTER ; G. DUCOUTUMANY ; C. VANSTEENE ; J. B. TRABUT ; P. GORWOOD ; C. DUBERTRET ; J. MATTA ; A. CHARLES-NELSON ; F. LIMOSIN |OBJECTIVE: Alcohol withdrawal syndrome (AWS) is a frequent and potentially life-threatening condition experienced in alcohol use disorder. Since hypomagnesemia is involved in AWS's severity, we conducted a multicenter double-blind randomized pla[...]Périodique
R. S. SCHOTTENFELD ; M. C. CHAWARSKI ; MAZLAN M. | 2008ENGLISH : BACKGROUND: Expansion of access to effective treatments for heroin dependence is a worldwide health priority that will also reduce HIV transmission. We compared the efficacy of naltrexone, buprenorphine, and no additional treatment, [...]Article : Périodique
S. LARNEY ; H. JONES ; T. RHODES ; M. HICKMAN |Epidemiology is a core discipline generating evidence to inform and drive drug policy. In this essay, we speculate on what the future of drug epidemiology might become. We highlight for attention two areas shaping the future of drug epidemiology[...]Article : Périodique
Background: Marijuana use is common among U.S. college students. Liberalization of marijuana use policies is hypothesized to decrease social norms discouraging use, which protects against marijuana use. This may increase the importance of protec[...]Bulletin : Périodique
Addiction, Vol.107, Suppl.1 - November 2012 - Maternal Opioid Treatment: Human Experimental Research (MOTHER) Study
E. S. BANDSTRA, Éditeur scientifique | 2012CONTENTS: • Maternal Opioid Treatment: Human Experimental Research (MOTHER) Study: maternal, fetal and neonatal outcomes from secondary analyses. Bandstra E.S., p. 1-4. • Buprenorphine treatment of opioid-dependent pregnant women: a comprehens[...]Article : Périodique
BACKGROUND: Many adolescents receive mentoring. There is no systematic review if mentoring prevents alcohol and drug use. OBJECTIVES: Assess effectiveness of mentoring to prevent adolescent alcohol/drug use. SEARCH METHODS: Cochrane CENTRAL [...]Article : Périodique
M. P. CARRIERI ; L. MICHEL ; C. LIONS ; J. COHEN ; M. VRAY ; M. MORA ; F. MARCELLIN ; B. SPIRE ; A. MOREL ; P. ROUX ; The Methaville Study Group |Objective: Methadone coverage is poor in many countries due in part to methadone induction being possible only in specialized care (SC). This multicenter pragmatic trial compared the effectiveness of methadone treatment between two induction mod[...]Article : Périodique
R. P. MATTICK ; C. BREEN ; J. KIMBER ; M. DAVOLI |Background: Methadone maintenance was the first widely used opioid replacement therapy to treat heroin dependence, and it remains the best-researched treatment for this problem. Despite the widespread use of methadone in maintenance treatment fo[...]Article : Périodique
A. SCHNEEGANS ; F. BOURGOGNON ; E. ALBUISSON ; R. SCHWAN ; M. ARFA ; L. POLLI ; M. MOULARD ; V. LAPREVOTE ; T. SCHWITZER |FRANÇAIS : Les approches basées sur la pleine conscience ont montré leur efficacité chez les patients atteints de troubles liés à la consommation de substances. La prévention des rechutes basée sur la pleine conscience (MBRP) intègre les pratiq[...]Article : Périodique
G. SMEDSLUND ; R. C. BERG ; K. T. HAMMERSTROM ; A. STEIRO ; K. A. LEIKNES ; H. M. DAHL ; K. KARLSEN |ENGLISH: BACKGROUND: There are 76.3 million people with alcohol use disorders worldwide and 15.3 million with drug use disorders. Motivational interviewing (MI) is a client-centred, semi-directive method for enhancing intrinsic motivation to ch[...]Article : Périodique
H. RIGTER ; C. E. HENDERSON ; I. PELC ; P. TOSSMANN ; O. PHAN ; V. HENDRIKS ; M. SCHAUB |Background: Noticing a lack of evidence-based programmes for treating adolescents heavily using cannabis in Europe, government representatives from Belgium, France, Germany, The Netherlands, and Switzerland decided to have U.S.-developed multidi[...]Article : Périodique
C. WERCH ; M. J. MOORE ; C. C. DICLEMENTE ; R. BLEDSOE ; E. JOBLI |The primary purpose of this study was to test the efficacy of a brief, multi-health behavior intervention integrating physical activity and alcohol use prevention messages for high school-aged adolescents. A total of 604 participants, 335 9th an[...]Périodique
R. Q. SKRABEK ; L. GALLMOVA ; K. ETHANS ; D. PERRY | 2008A randomized, double-blind, placebo-controlled trial was conducted to determine the benefit of nabilone in pain management and quality of life improvement in 40 patients with fibromyalgia. After a baseline assessment, subjects were titrated up o[...]Article : Périodique
N. LINTZERIS ; A. BHARDWAJ ; L. MILLS ; A. DUNLOP ; J. COPELAND ; I. MCGREGOR ; R. BRUNO ; J. GUGUSHEFF ; N. PHUNG ; M. MONTEBELLO ; T. CHAN ; A. KIRBY ; M. HALL ; M. JEFFERIES ; J. LUKSZA ; M. SHANAHAN ; R. KEVIN ; D. ALLSOP ; Agonist Replacement for Cannabis Dependence study group |ENGLISH: Importance: There are no effective medications for treating dependence on cannabis. Objective: To examine the safety and efficacy of nabiximols in the treatment of patients with cannabis dependence. Design, Setting, and Participants:[...]Article : Périodique
H. E. JONES ; K. KALTENBACH ; S. H. HEIL ; S. M. STINE ; M. G. COYLE ; A. M. ARRIA ; K. E. O'GRADY ; P. SELBY ; P. R. MARTIN ; G. FISCHER |Background: Methadone, a full mu-opioid agonist, is the recommended treatment for opioid dependence during pregnancy. However, prenatal exposure to methadone is associated with a neonatal abstinence syndrome (NAS) characterized by central nervou[...]Article : Périodique
N. WALKER ; V. PARAG ; M. VERBIEST ; G. LAKING ; M. LAUGESEN ; C. BULLEN |Background: Combination nicotine replacement therapy shows additive cessation benefits. We aimed to find out the effectiveness of combining nicotine patches with an e-cigarette (with and without nicotine) on six-month smoking abstinence. Method[...]Article : Périodique
L. F. STEAD ; R. PERERA ; C. BULLEN ; D. MANT ; T. LANCASTER |BACKGROUND: The aim of nicotine replacement therapy (NRT) is temporarily to replace much of the nicotine from cigarettes to reduce motivation to smoke and nicotine withdrawal symptoms, thus easing the transition from cigarette smoking to complet[...]Article : Périodique
A. WHITE ; D. KAVANAGH ; H. STALLMAN ; B. KLEIN ; F. KAY-LAMBKIN ; J. PROUDFOOT ; J. DRENNAN ; J. CONNOR ; A. BAKER ; E. HINES ; R. YOUNG |BACKGROUND: There has been a significant increase in the availability of online programs for alcohol problems. A systematic review of the research evidence underpinning these programs is timely. OBJECTIVES: Our objective was to review the effi[...]Article : Périodique
R. P. SCHWARTZ ; S. M. KELLY ; S. G. MITCHELL ; J. GRYCZYNSKI ; K. E. O'GRADY ; D. GANDHI ; Y. OLSEN ; J. H. JAFFE |Background and Aims: Methadone patients who discontinue treatment are at high risk of relapse, yet a substantial proportion discontinue treatment within the first year. We investigated whether a patient-centered approach to methadone treatment i[...]Périodique
R. S. GARFEIN ; E. T. GOLUB ; A. E. GREENBERG ; H. HAGAN ; D. L. HANSON ; S. M. HUDSON ; F. KAPADIA ; M. H. LATKA ; L. J. OUELLET ; D. W. PURCELL ; S. A. STRATHDEE ; H. THIEDE | 2007OBJECTIVES: To evaluate whether a behavioral intervention, which taught peer education skills, could reduce injection and sexual risk behaviors associated with primary HIV and hepatitis C virus infection (HCV) among young injection drug users (I[...]Article : Périodique
Objective: A small body of evidence supports targeting adolescents who are heavy users of cannabis with brief interventions, yet more research is needed to confirm the effectiveness of these studies. We conducted a secondary analysis of our Peer[...]Article : Périodique
Article : Périodique
BACKGROUND: Personality factors are implicated in the vulnerability to adolescent alcohol misuse. This study examined whether providing personality-targeted interventions in early adolescence can delay drinking and binge drinking in high-risk yo[...]Article : Périodique
A. E. PERRY ; M. NEILSON ; M. MARTYN-ST JAMES ; J. M. GLANVILLE ; R. WOODHOUSE ; C. GODFREY ; C. HEWITT |Background: The review represents one in a family of four reviews focusing on a range of different interventions for drug-using offenders. This specific review considers pharmacological interventions aimed at reducing drug use or criminal activi[...]Article : Périodique
A. ARAIN ; J. DE SOUSA ; K. CORTEN ; R. VERRANDO ; H. THIJS ; C. MATHEI ; F. BUNTINX ; G. ROBAEYS |Background: Treatment uptake for hepatitis C virus (HCV) infection remains low in persons who inject drugs (PWID), due to lack of knowledge and low perceived need for treatment. Therefore, we conducted a pilot study to assess the influence on kn[...]Article : Périodique
ENGLISH : Aims: To assess the feasibility of conducting an RCT comparing buprenorphine and methadone maintenance therapy in Norfolk. Design: Forty-two opiate dependent patients were given the option of being randomized or choosing between open[...]Article : Périodique
AIMS This study conducted a secondary analysis to examine injection cessation and decreasing frequency of injection during a multi-site randomized controlled HIV prevention intervention trial that sought to reduce sexual and injection risk behav[...]Article : Périodique
Young adults in college have high rates of marijuana use, abuse, and dependence. Web-based interventions are increasingly popular, but their dissemination exceeds empirical support. One popular but understudied program is The Marijuana eCHECKUP [...]Article : Périodique
BACKGROUND AND AIMS: The prevalence of cannabis use based on self-reports is likely to be underestimated in population surveys, especially in contexts where its use is a criminal offence. Indirect survey methods ask sensitive questions ensuring [...]Article : Périodique
There are many mandated school-based programs to prevent adolescent alcohol and drug (AOD) use, but few are voluntary and take place outside of class time. Objectives: This cluster randomized controlled trial evaluates CHOICE, a voluntary after[...]Article : Périodique
H. F. BYRNES ; B. A. MILLER ; B. BOURDEAU ; M. B. JOHNSON ; D. B. BULLER ; J. BERTELETTI ; V. A. ROGERS |Objective: Electronic music dance events (EMDEs) at nightclubs attract young adults engaging in high-risk alcohol and other drug (AOD) use. Studies show that most patrons arrive at clubs in groups and that these peer groups influence drinking. T[...]Article : Périodique
H. F. BYRNES ; B. A. MILLER ; J. W. GRUBE ; B. BOURDEAU ; D. B. BULLER ; M. WANG-SCHWEIG ; W. G. WOODALL |This study examines effects of a randomized controlled trial for an online, family-based prevention program for older teens, Smart Choices 4 Teens, on alcohol use and related outcomes. Families (N = 411; teen age M = 16.4, SD = 0.5) were randoml[...]Article : Périodique
A. A. MOORE ; F. C. BLOW ; M. HOFFING ; S. WELGREEN ; J. W. DAVIS ; J. C. LIN ; K. D. RAMIREZ ; D. H. LIAO ; L. TANG ; R. GOULD ; M. GILL ; O. CHEN ; K. L. BARRY |AIMS: To examine whether a multi-faceted intervention among older at-risk drinking primary care patients reduced at-risk drinking and alcohol consumption at 3 and 12 months. DESIGN: Randomized controlled trial. SETTING: Three primary care sites [...]Rapport
Université de Liège ; I. DEMARET ; G. LITRAN ; C. MAGOGA ; C. DEBLIRE ; J. DE ROUBAIX ; E. QUERTEMONT ; D. VAN CAILLIE ; N. DUBOIS ; A. LEMAITRE ; M. ANSSEAU | Université de Liège | 2013Le projet - historique et protocole : Ce projet, qui était en discussion à Liège depuis 1995, a fait l'objet d'un accord définitif en février 2007, date à laquelle les ministres fédéraux de la Santé publique et de la Justice ont annoncé le lanc[...]Article : Périodique
C. BEN LAKHDAR ; A. DEPLANCKE ; F. LE LEC ; S. MASSIN ; A. PIERMATTEO ; N. VAILLANT |INTRODUCTION: Tobacco smoking is one of the leading causes of preventable death. This is not inevitable as tobacco control tools have become more powerful and more effective. Among these, warnings on cigarette packs have proven to be somewhat ef[...]Article : Périodique
G. GMEL ; V. VENZIN ; K. MARMET ; G. DANKO ; F. LABHART |Objectives: To show the effectiveness of a brief group alcohol intervention. Aims of the intervention were to reduce the frequency of heavy drinking occasions, maximum number of drinks on an occasion and overall weekly consumption. Methods: A c[...]Périodique
N. HEATHER ; BOWIE A. ; H. ASHTON ; MC AVOY B. ; I. SPENCER ; BRODIE J. ; GIDDINGS D. | 2004ENGLISH : Previous studies have reported that a letter from the patient's General Practitioner (GP) and a short GP consultation led to reduced intake among long-term benzodiazepine (BZD) users, with no evidence of a deterioration in general or[...]Article : Périodique
L. M. ROBERTS ; S. WILSON ; A. ROALFE ; P. BRIDGE |BACKGROUND: Postal questionnaires are an economical and simple method of data collection for research purposes but are subject to non-response bias. Several studies have explored the effect of monetary and non-monetary incentives on response. Re[...]Article : Périodique
BACKGROUND: A well designed randomized clinical trial rates as the highest level of evidence for a particular intervention's efficacy. Randomization, a fundamental feature of clinical trials design, is a process invoking the use of probability t[...]Article : Périodique
A. SPIRITO ; P. M. MONTI ; N. P. BARNETT ; S. M. COLBY ; H. SINDELAR ; D. J. ROHSENOW ; W. LEWANDER ; M. MYERS |We tested whether a brief motivational interview (MI) would reduce alcohol-related consequences and use among adolescents treated in an emergency department (ED) after an alcohol-related event. Patients aged 13 to 17 years (N = 152) with a posit[...]Article : Périodique
R. HUMENIUK ; R. ALI ; T. F. BABOR ; M. L. SOUZA FORMIGONI ; R. B. DE LACERDA ; W. LING ; B. McREE ; D. NEWCOMBE ; H. PAL ; V. POZNYAK ; S. SIMON ; J. VENDETTI |AIMS: This study evaluated the effectiveness of a brief intervention (BI) for illicit drugs (cannabis, cocaine, amphetamine-type stimulants and opioids) linked to the World Health Organization (WHO) Alcohol, Smoking and Substance Involvement Scr[...]Article : Périodique
D. D. WALKER ; R. STEPHENS ; R. ROFFMAN ; J. DEMARCE ; B. LOZANO ; S. TOWE ; B. BERG |AIMS: Cannabis use adversely affects adolescents and interventions that are attractive to adolescents are needed. This trial compared the effects of a brief motivational intervention for cannabis use with a brief educational feedback control and[...]Article : Périodique
ENGLISH: Aim: We tested the efficacy of a brief intervention based on motivational interviewing (MI) to reduce high-risk injection behaviours over a 6-month period among people who inject drugs (PWID). Design: A single-site two-group parallel [...]Article : Périodique
Aims: To evaluate the efficacy of a telephone-based intervention consisting of four sessions of motivational interviewing (MI) and cognitive behavioural therapy (CBT) designed to assist individuals to reduce their cannabis use and related proble[...]Article : Périodique
M. A. WALTON ; S. RESKO ; K. L. BARRY ; S. T. CHERMACK ; R. A. ZUCKER ; M. A. ZIMMERMAN ; B. M. BOOTH ; F. C. BLOW |Aims: To examine the efficacy of a brief intervention delivered by a therapist (TBI) or a computer (CBI) in preventing cannabis use among adolescents in urban primary care clinics. Design: A randomized controlled trial comparing: CBI and TBI v[...]Article : Périodique
D. M. DOUMAS ; S. ESP ; B. FLAY ; L. BOND |OBJECTIVE: The purpose of this randomized controlled study was to examine the efficacy of a brief, web-based personalized feedback intervention (the eCHECKUP TO GO) on alcohol use and alcohol-related consequences among high school seniors. METH[...]Livre
Randomized controlled trials are one of the most powerful and revolutionary tools of research. This book is a convenient and accessible description of the underlying principles and practice of randomized controlled trials and their role in clini[...]Article : Périodique
M. REYNAUD ; H. J. AUBIN ; F. TRINQUET ; B. ZAKINE ; C. DANO ; M. DEMATTEIS ; B. TROJAK ; F. PAILLE ; M. DETILLEUX |Aims: Alcohol dependence is a major public health issue with a need for new pharmacological treatments. The ALPADIR study assessed the efficacy and safety of baclofen at the target dose of 180 mg/day for the maintenance of abstinence and the red[...]Article : Périodique
P. HAJEK ; A. PHILLIPS-WALLER ; D. PRZULJ ; F. PESOLA ; K. MYERS SMITH ; N. BISAL ; J. LI ; S. PARROTT ; P. SASIENI ; L. DAWKINS ; L. ROSS ; M. GONIEWICZ ; Q. WU ; H. J. MCROBBIE |Background: E-cigarettes are commonly used in attempts to stop smoking, but evidence is limited regarding their effectiveness as compared with that of nicotine products approved as smoking-cessation treatments. Methods: We randomly assigned adu[...]Article : Périodique
M. McKENZIE ; N. ZALLER ; S. L. DICKMAN ; T. C. GREEN ; A. PARIHK ; P. D. FRIEDMANN ; J. D. RICH |Individuals who use heroin and illicit opioids are at high risk for infection with human immunodeficiency virus (HIV) and other blood-borne pathogens, as well as incarceration. The purpose of the randomized trial reported here is to compare outc[...]Article : Périodique
T. COLEMAN ; S. COOPER ; J. G. THORNTON ; M. J. GRAINGE ; K. WATTS ; J. BRITTON ; S. LEWIS ; Smoking, Nicotine, and Pregnancy (SNAP) Trial Team |Background: Nicotine-replacement therapy is effective for smoking cessation outside pregnancy and its use is widely recommended during pregnancy. We investigated the efficacy and safety of nicotine patches during pregnancy. Methods: We recruite[...]Article : Périodique
H. REDDON ; T. KERR ; M. J. MILLOY |Evidence-based medicine has consistently prized the epistemological value of randomized-controlled trials (RCTs) owing to their methodological advantages over alternative designs such as observational studies. However, there are limitations to R[...]Article : Périodique
E. F. KANER ; LOCK C. A. ; McAVOY B. R. ; N. HEATHER ; E. GILVARRY |BACKGROUND: Providing doctors with new research findings or clinical guidelines is rarely sufficient to promote changes in clinical practice. An implementation strategy is required to provide clinicians with the skills and encouragement needed t[...]Article : Périodique
Injection drug initiation usually requires assistance by someone who already injects drugs. To develop interventions that prevent people from starting to inject drugs, it is imperative to understand why people who inject drugs (PWID) assist with[...]Article : Périodique
T. W. KIM ; J. BERNSTEIN ; D. M. CHENG ; C. LLOYD-TRAVAGLINI ; J. H. SAMET ; T. P. PALFAI ; R. SAITZ |Background and Aims: Screening, brief intervention and 'referral to treatment' programs have been promoted widely as US federal policy. Little is known about the efficacy of the RT component (referral to treatment) of brief intervention for moti[...]Article : Périodique
Les neurosciences ont révélé qu'à l'adolescence le cerveau humain subit encore des processus de maturation très importants jusqu'à environ 25 ans. L'âge des premières ivresses est en France aux alentours de 15 ans et ces premières ivresses peuve[...]