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ETUDE CLINIQUE |
Documents disponibles dans cette catégorie (196)
Article : Périodique
B. BRUNET ; Y. JAGAILLOUX ; P. PALAZZO ; J. LELONG ; P. MURA ; J. P. NEAU |FRANÇAIS : Notre étude a pour but d'évaluer la prévalence d'usage de stupéfiants parmi les victimes d'AVC (accidents vasculaires cérébraux) et AIT (accidents ischémiques transitoires) âgées de moins de 55 ans. La première partie de cette étude [...]Article : Périodique
Les prescriptions de baclofène en dehors de ses indications (neurologiques) augmentent.Article : Périodique
FRANÇAIS : À travers une réflexion sur les « contraintes par corps », sur le statut du toxique en tant que pharmakon (à la fois poison et remède), ainsi que sur les « identifications addictives inconscientes », l'auteur interroge la manière don[...]Article : Périodique
FRANÇAIS : L'état bucco-dentaire des patients rencontrés en service d'addictologie est souvent préoccupant. Soigner les dents efficacement et sur la durée est difficile. Quelles en sont les causes ? Est-ce une conséquence de la prise de toxique[...]Article : Périodique
G. DORARD ; S. BERTHOZ ; O. PHAN ; M. CORCOS ; C. BUNGENER |Psychiatric comorbidity and impaired emotional functioning have been previously reported in adult substance abusers but have been less well documented in adolescents. Thus, we investigated mental health problems and emotion regulation abilities [...]Article : Périodique
FRANÇAIS : Introduction. Les conséquences pour le développement foetal d'une exposition à l'alcool in utero varient en fonction de l'intensité de l'exposition. Il n'a pas été mis en évidence une dose -seuil en deçà de laquelle une consommation [...]Article : Périodique
Route of administration is an important contributor to the adverse health consequences of prescription medication abuse. The current study examines characteristics associated with non-oral routes of administration among a large sample of prescri[...]Article : Périodique
S. LEVY ; R. WEISS ; L. SHERRITT ; R. ZIEMNIK ; A. SPALDING ; S. VAN HOOK ; L. A. SHRIER |IMPORTANCE: Screening adolescents for substance use and intervening immediately can reduce the burden of addiction and substance-related morbidity. Several screening tools have been developed to identify problem substance use for adolescents, bu[...]Article : Périodique
S. J. ADAMSON ; F. J. KAY-LAMBKIN ; A. L. BAKER ; T. J. LEWIN ; L. THORNTON ; B. J. KELLY ; J. D. SELLMAN |BACKGROUND: Cannabis is widely used and significant problems are associated with heavier consumption. When a cannabis misuse screening tool, the CUDIT, was originally published it was noted that although it performed well there was concern about[...]Article : Périodique
D. S. HASIN ; M. C. FENTON ; C. BESELER ; J. Y. PARK ; M. M. WALL |BACKGROUND: A number of changes have been proposed and investigated in the criteria for substance use disorders in DSM-5. However, although clinical utility of DSM-5 is a high priority, relatively little of the empirical evidence supporting the [...]Article : Périodique
C. DENIS ; M. FATSEAS ; M. AURIACOMBE |BACKGROUND: The DSM-5 Substance-Related Disorders Work Group proposed to include Pathological Gambling within the current Substance-Related Disorders section. The objective of the current report was to assess four possible sets of diagnostic cri[...]Article : Périodique
M. MEINI ; M. MONCINI ; D. CECCONI ; V. CELLESI ; L. BIASCI ; G. SIMONI ; M. AMEGLIO ; M. PELLEGRINI ; R. N. FORGIONE ; P. RUCCI |BACKGROUND: Currently, there is no specific pharmacological therapy with established efficacy for the treatment of cocaine dependence. The aim of this study was to determine the safety, tolerability and the effects of aripiprazole and ropinirole[...]Article : Périodique
O. PHAN ; J. P. COUTERON ; N. BASTARD ; C. BONNAIRE |FRANÇAIS : Pour aborder la question de la consommation de drogue à l'adolescence, le modèle multidimensionnel est spécialement fructueux. Il postule qu'il n'existe pas une cause de la consommation, mais des facteurs favorisants et protecteurs q[...]Article : Périodique
Gay and bisexual men and other men who have sex with men (GBMSM) with problematic chemsex (a specific sexualized drug use pattern) face several health issues. The aim of this monocentric observational study was to assess the mental health histor[...]Article : Périodique
G. BUTLER ; D. CHAPMAN ; P. TERRY |Aim: The study investigated the attitudes of intravenous drug users (IDUs) towards the provision of drug consumption rooms (DCRs) in the UK and their willingness to use DCRs. Methods: Participants were 90 methadone-maintained outpatients recrui[...]Rapport
Article : Périodique
S. E. ZEMORE ; O. D. WARE ; P. A. GILBERT ; M. PINEDO |Purpose: Few studies and no theory-based scales have addressed specific barriers to substance use disorder (SUD) treatment retention. The current study, building on the Theory of Planned Behavior (TPB), sought to (a) identify those barriers that[...]Article : Périodique
V. WAGNER ; D. ACIER ; J. E. DIETLIN |Gaining a better grasp on factors related to changes in alcohol use is of particular interest for clinicians. Past research has highlighted a negative link between future time perspective (i.e. a disposition guiding how individuals consider and [...]Article : Périodique
We randomized 332 women, 18-24 years old, who were not explicitly seeking treatment for their marijuana use to either a two-session motivationally focused intervention or an assessment-only condition. Assessed by timeline follow-back methodology[...]Périodique
M. F. FLEMING ; K. LAWTON BARRY ; MANWELL L. B. ; K. JOHNSON ; LONDON R. | 1997ENGLISH : Objective. - Project TrEAT (Trial for Early Alcohol Treatment) was designed to test the efficacy of brief physician advice in reducing alcohol use and health care utilization in problem drinkers. Design. - Randomized controlled clini[...]Article : Périodique
M. GUILLOU-LANDREAT ; V. SEBILLE-RIVAIN ; C. VICTORRI-VIGNEAU ; Y. FOUCHER ; J. L. VENISSE ; P. JOLLIET |Introduction: Buprenorphine is one of the main opioid dependence treatments, especially in France, where it has been widely prescribed since 1996. But it can easily be misused and its prescription has to be followed up. In the literature, we fou[...]Article : Périodique
M. HANEY ; A. S. WARD ; S. D. COMER ; C. L. HART ; R. W. FOLTIN ; M. W. FISCHMAN |RATIONALE: Symptoms of withdrawal after daily marijuana smoking include increased ratings of irritability and depression. Similar mood symptoms are reported by cigarette smokers during nicotine abstinence. OBJECTIVE: Given the successful use o[...]Article : Périodique
E. GUILLEM ; C. NOTIDES ; F. VORSPAN ; M. DEBRAY ; I. NIETO ; M. LEROUX ; J. P. LEPINE |The aim of this study was to evaluate the psychometric properties of the French version of the Marijuana Effect Expectancy Questionnaire (48 items) and study the cannabis expectancies according to the patterns of substance use and psychiatric di[...]Article : Périodique
M. LEJOYEUX ; A. BASQUIN ; M. KOCH ; H. EMBOUAZZA ; F. CHALVIN ; M. ILONGO |Background: To assess the prevalence of cannabis use and dependence in a population of schizophrenic inpatients and to compare schizophrenics with and without cannabis consumption. Methods: One hundred one schizophrenic patients were examined d[...]Article : Périodique
D. J. FOTI ; R. KOTOV ; L. T. GUEY ; E. J. BROMET |OBJECTIVE: The authors examined the relationship between cannabis use and the course of illness in schizophrenia over 10 years of follow-up after first psychiatric hospitalization. METHOD: The authors assessed 229 patients with a schizophrenia s[...]Article : Périodique
M. AUFFRET ; B. ROLLAND ; H. BEHAL ; J. LABREUCHE ; E. JOUANJUS ; R. BORDET ; S. GAUTIER |The local/regional incidence of off-label prescriptions can be difficult to estimate. Capture-recapture models can be used to indirectly estimate population sizes. Here, we used a capture-recapture model to estimate the number of patients treate[...]Article : Périodique
L. CLAUSEN ; C. R. HJORTHOJ ; A. THORUP ; P. JEPPESEN ; L. PETERSEN ; M. BERTELSEN ; NORDENTOFT M. |BACKGROUND: Several studies indicate that cannabis use among patients with psychotic disorders is associated with worse outcome, but only a few studies have controlled for baseline condition and medication. Method At 5-year follow-up, interviews[...]Article : Périodique
Aims: To test (1) whether abstinence and reduction in illicit psychoactive drug use were associated with changes in health outcomes in primary care patients and (2) whether these associations varied by drug type. Design: Secondary analysis of d[...]Article : Périodique
C. PAYAN ; F. ROUDOT-THORAVAL ; P. MARCELLIN ; N. BLED ; G. DUVERLIE ; I. FOUCHARD-HUBERT ; P. TRIMOULET ; P. COUZIGOU ; D. COINTE ; C. CHAPUT ; C. HENQUELL |This cross-sectional study aimed to investigate, during a short period between 2000 and 2001, in a large population of patients with chronic hepatitis C, the epidemiological characteristics of hepatitis C virus (HCV) genotypes in France. Data fr[...]Article : Périodique
C. EVREN ; B. EVREN ; E. DALBUDAK ; B. OZCELIK ; F. ONCU |The prevalence of childhood abuse and neglect (CAN) histories and their associations with alexithymia among male substance-dependent inpatients were studied. Participants were 159 consecutively admitted male substance dependents (115 alcohol and[...]Article : Périodique
R. SAITZ ; D. M. CHENG ; M. WINTER ; T. W. KIM ; S. M. MELI ; D. ALLENSWORTH-DAVIES ; C. LLOYD-TRAVAGLINI ; J. H. SAMET |Importance: People with substance dependence have health consequences, high health care utilization, and frequent comorbidity but often receive poor-quality care. Chronic care management (CCM) has been proposed as an approach to improve care and[...]Article : Périodique
BACKGROUND AND AIMS: The pathways model is a highly cited etiological model of problem gambling. In the past two decades, a number of studies have found support for the model's utility in classifying gambling subtypes. The aims of this paper wer[...]Article : Périodique
M. MIDE ; E. ARVIDSON ; A. S. GORDH |INTRODUCTION: Gambling disorder (GD) is classified among the addictive disorders in the DSM-5 and the severity of the diagnosis can be specified as mild, moderate and severe. It has been seen that individuals with more severe gambling problems h[...]Article : Périodique
H. J. AUBIN ; J. REIMER ; D. J. NUTT ; A. BLADSTROM ; L. TORUP ; C. FRANÇOIS ; J. CHICK |Nalmefene is the first drug approved for reduction of alcohol consumption. The aim of this study was to evaluate the clinical relevance of treatment with nalmefene in alcohol-dependent patients with a high drinking risk level from two randomised[...]Article : Périodique
Background: The published ambulance referral criteria (ARC) for assessing individuals with acute recreational drug toxicity in the prehospital setting consist of nine domains. The ARC recommend that an ambulance is called to transfer those with [...]Article : Périodique
C. SKOGLUND ; U. HERMANSSON ; O. BECK |Exhaled breath has recently been proposed as a matrix for drug testing. This study aims to further explore, develop and validate exhaled breath as a safe and effective non-invasive method for drug testing in a clinical setting. Self-reported dru[...]Livre
This comprehensive, unified text on the principles and practice of clinical trials presents a detailed account of how to conduct the trials. It describes the design, analysis, and interpretation of clinical trials in a non-technical manner and p[...]Article : Périodique
BACKGROUND: Chronic stimulant use can produce a paranoid psychosis that is similar to acute paranoid schizophrenia. While this phenomenon has been systematically explored in amphetamine abusers, it has been relatively unexplored in a systematic [...]Article : Périodique
F. VORSPAN ; G. BROUSSE ; V. BLOCH ; L. BELLAIS ; L. ROMO ; E. GUILLEM ; P. COEURU ; J. P. LEPINE |Cocaine use is known to induce transient psychotic symptoms. We evaluated retrospectively the lifetime prevalence of cocaine-induced psychotic symptoms in 105 cocaine addicts with the French version of the Scale for Assessment of Positive Sympto[...]Article : Périodique
FRANÇAIS : Revue de dossiers de patients pour étudier les cas de lésions musculaires après cocaine: sept cas sont trouvés de Juin 87 à Juin 88. Ils se présentent tous une heure après une prise de cocaine base avec douleur au niveau des muscles[...]Article : Périodique
FRANÇAIS : Une étude rétrospective de six mois sur 233 toxicomanes venus dans un service d'urgence a permis de décrire les complications liées à la cocaïne. Les caractéristiques de la population, les voies d'administration de la cocaïne et la f[...]Article : Périodique
L. J. MOONEY ; S. NIELSEN ; A. SAXON ; M. HILLHOUSE ; C. THOMAS ; A. HASSON ; D. STABLEIN ; J. McCORMACK ; R. LINDBLAD ; W. LING |BACKGROUND: Effective medications to treat cocaine dependence have not been identified. Recent pharmacotherapy trials demonstrate the potential efficacy of buprenorphine (BUP) (alone or with naltrexone) for reducing cocaine use. The National Ins[...]Article : Périodique
Aims: Electronic health records (EHRs) are essential in improving quality and enhancing efficiency of health-care delivery. By 2015, medical care receiving service reimbursement from US Centers for Medicare and Medicaid Services (CMS) must show [...]Article : Périodique
J. RACZ ; K. MELLES ; F. MARVANYKOVI ; M. LENCSE ; Z. PETKE |Aims: Drug use is an indictable offence in Hungary, but there is an opportunity to suspend the criminal proceedings if a small quantity of drugs is involved. However, the principle of 'treatment instead of punishment' (TIP) is heavily disputed i[...]Article : Périodique
FRANÇAIS : Les diagnostics d'abus, de dépendance (DSM-IV) et de troubles psychiatriques (Mini-International Neuropsychiatric Interview) ont été portés chez 207 usagers de cannabis (71 % hommes, 29,3 ± 8,6 ans) vus en « consultation jeunes conso[...]Article : Périodique
S. E. BACK ; R. L. PAYNE ; A. H. WAHLQUIST ; R. E. CARTER ; Z. STROUD ; L. HAYNES ; M. HILLHOUSE ; K. T. BRADY ; W. LING |Background: Accumulating evidence indicates important gender differences in substance use disorders. Little is known, however, about gender differences and opioid use disorders. Objectives: To compare demographic characteristics, substance use s[...]Article : Périodique
Recent studies have demonstrated the therapeutic potential of cannabinoids to treat pain, yet none have compared the analgesic effectiveness of smoked marijuana to orally administered Δ9-tetrahydrocannabinol (THC; dronabinol). This randomized, p[...]Article : Périodique
FRANÇAIS : Contexte : cet article relate une démarche de dépistage, d'information et de prévention autour des consommations abusives de caféine (plus de 300 mg) chez 25 sujets rencontrés dans une unité d'addictologie hospitalière. Méthodes : ce[...]Article : Périodique
L. ROCHE ; D. RICHARD ; F. LIBERT ; J. PINGUET ; G. BROUSSE ; M. MIALOU ; J. DELORME ; C. CHENAF ; N. AUTHIER |FRANÇAIS : En dehors des essais cliniques relatifs aux 2 médicaments de substitution aux opiacés (MSO), la buprénorphine et la méthadone, et des enquêtes réalisées par le réseau des centres d'addictovigilance, nous disposons de très peu de donn[...]