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| Titre : | Frontiers in Psychiatry, Vol.9. - 2018 |
| Type de document : | Bulletin |
| Paru le : | 17/10/2018 |
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Article : Périodique
Baclofen, a GABA-B receptor agonist, is a promising treatment for alcohol use disorder (AUD). Its mechanism of action in this condition is unknown. GABA-B receptors interact with many biological systems potentially involved in AUD, including tra[...]
Article : Périodique
R. DE BEAUREPAIRE ;
J. M. A. SINCLAIR ;
M. HEYDTMANN ;
G. ADDOLORATO ;
H. J. AUBIN ;
E. M. BERAHA ;
F. CAPUTO ;
J. D. CHICK ;
P. DE LA SELLE ;
N. FRANCHITTO ;
J. C. GARBUTT ;
P. S. HABER ;
P. JAURY ;
A. R. LINGFORD-HUGHES ;
K. C. MORLEY ;
C. A. MULLER ;
L. OWENS ;
A. PASTOR ;
L. M. PATERSON ;
F. PELISSIER ;
B. ROLLAND ;
A. STAFFORD ;
A. THOMPSON ;
W. VAN DEN BRINK ;
L. LEGGIO ;
R. AGABIO
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Alcohol use disorder (AUD) is a brain disorder associated with high rates of mortality and morbidity worldwide. Baclofen, a selective gamma-aminobutyric acid-B (GABA-B) receptor agonist, has emerged as a promising drug for AUD. The use of this d[...]
