Future Medicinal Chemistry, Vol.4, n°2. Drugs of abuse and treatment of addiction - February 2012
Titre : | Future Medicinal Chemistry, Vol.4, n°2. Drugs of abuse and treatment of addiction - February 2012 |
Type de document : | Bulletin |
Paru le : | 01/02/2012 |
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Are pharmacokinetic approaches feasible for treatment of cocaine addiction and overdose? [Editorial]
F. ZHENG ;
C. G. ZHAN
|
2012
Dans Future Medicinal Chemistry (Vol.4, n°2, February 2012) Article : Périodique
Dans Future Medicinal Chemistry (Vol.4, n°2, February 2012) Article : Périodique
We discuss the main challenges for developing therapeutic treatment of cocaine addiction and explain why pharmacokinetic approaches, particularly those based on our recently developed efficient cocaine-metabolizing enzymes, are feasible for trea[...]

J. B. WANG ;
J. R. MANTSCH
|
2012
Dans Future Medicinal Chemistry (Vol.4, n°2, February 2012) Article : Périodique
Dans Future Medicinal Chemistry (Vol.4, n°2, February 2012) Article : Périodique
Levo-tetrahydropalmatine (l-THP) is an active constituent of herbal preparations containing plant species of the genera Stephania and Corydalis and has been approved and used in China for a number of clinical indications under the drug name Rotu[...]

C. W. SCHINDLER ;
S. R. GOLDBERG
|
2012
Dans Future Medicinal Chemistry (Vol.4, n°2, February 2012) Article : Périodique
Dans Future Medicinal Chemistry (Vol.4, n°2, February 2012) Article : Périodique
One pharmacokinetic approach to the treatment of cocaine abuse and toxicity involves the development of compounds that can be safely administered to humans and that accelerate the metabolism of cocaine to inactive components. Catalytic antibodie[...]