| Titre : | Journal of Child and Adolescent Substance Abuse, Vol.10, n°4 - 2001 - Etiology of substance use disorder in children and adolescents: emerging findings from the center for education and drug abuse research |
| Auteurs : | R. E. TARTER ; M. M. VANYUKOV |
| Type de document : | Bulletin : Périodique |
| Paru le : | 01/04/2001 |
| Année de publication : | 2001 |
| Format : | 134 p. |
| Langues: | Anglais |
| Discipline : | PSY (Psychopathologie / Psychopathology) |
| Mots-clés : |
Thésaurus mots-clés ENFANT ; ETIOLOGIE ; ADOLESCENT ; CONSOMMATION ; RECHERCHE DE SENSATION ; TABAC ; CLASSIFICATION ; DEPENDANCE ; SEXE MASCULIN ; RELATION PARENT ENFANT ; FACTEUR DE VULNERABILITE |
| Résumé : | The compendium of articles in this monograph encompasses two interrelated themes currently emphasized in CEDAR's research. One line of research is directed at delineating the mechanisms underlying the development of a diagnosed substance use disorder (SUD). Genetic, biochemical, physiological, and psychological processes are investigated in conjunction with physical and social environment factors with the objective of elucidating the developmental pathway to SUD. Using a prospective paradigm the factors associated with the transition from no drug use to drug use to a diagnosis of abuse or dependence will be determined. Upon completion of this research, the individual's risk for transitioning from one phase to the next can be quantitatively specified. As documented in the various articles, the research findings accrued to date at CEDAR indicate that psychological dysregulation is an integral characteristic of SUD liability during childhood. The heuristic utility of this phenotype is underscored by emerging results demonstrating genetic (see Vanyukov et al.), biochemical (see Pajer et al.), maturational (see Kirillova et al.) and executive cognitive functioning influences (see Shoal and Giancola) on the expression of psychological dysregulation, which, in turn, predisposes to regular tobacco consumption during adolescence (see Reynolds et al.) and SUD by young adulthood (Tarter et al., submitted a). One important component of this research program pertains to delineating the factors that are specific to SUD liability in relation to comorbid outcomes such as suicide (see Cornelius et al.) and violence (Tarter et al., submitted b). A second line of research pertains to instrumentation development for practical and efficient assessment of the variables salient to SUD liability. Based on CEDAR's comprehensive protocols, several instruments have been provi- sionally developed. As discussed herein, these include a multidimensional measure of neglectful parenting (see Dunn et al.), a multidimensional schema for assessing substance use topology (see Kirisci and Tarter), a multi-informant questionnaire for assessing psychological dysregulation (see Mezzich et al.) and a multi-domain screening inventory of problems which commonly precede or emerge concomitant to substance use behavior (see Tarter and Kirisci). These instruments enhance clarification of SUD liability and potentially improve prediction accuracy of SUD outcome. Furthermore, investigations at CEDAR spearhead the application of diachronic evaluation; that is, assessment which is linked to discrete phases in the emergence of SUD (see Clark et al.). In the course of CEDAR's longitudinal research, technology transfer will thus be accomplished through development of new instrumentation designed to identify youth who are at high risk for SUD. In this fashion, prevention practice will be grounded in empirical research based on etiology of SUD. (Editor's abstract.) |
| Domaine : | Drogues illicites / Illicit drugs ; Tabac / Tobacco |
| Sous-type de document : | N° spécial de revue / Special issue of a journal |
| Affiliation : | USA |
| Numéro Toxibase : | 403843 |
| Centre Emetteur : | 04 CIRDD-51 |
| Cote : | Abonnement |
Dépouillements
Ajouter le résultat dans votre panierArticle : Périodique
The Center for Education and Drug Abuse Research (CEDAR), funded by the National Institute on Drug Abuse since 1989, has the overarching mission of delineating the origins and developmental pathways to Substance Use Disorder (SUD). This disorder[...]
Article : Périodique
D. B. CLARK ;
POLLOCK N. K. ;
A. MEZZICH ;
J. CORNELIUS ;
C. MARTIN
|
Substance use is a complex phenomenon that changes during the natural history of consumption. Relevant parameters encompass age of initiation, type and amount of drug consumed per episode, and problems resulting from substance consumption. Compr[...]
Article : Périodique
The purpose of this study was to design and evaluate a multidimensional schema for the assessment of alcohol, tobacco and other drug use topology. Six first order dimensions and a single second order dimension were confirmed. The first order dim[...]
Article : Périodique
Emerging evidence indicates that psychological dysregulation is an integral component of the liability for substance use disorder (SUD). To date, the measurement of dysregulation entails using a variety of disparate unstandardized instruments. T[...]
Article : Périodique
The Drug Use Screening Inventory (DUSI) has been shown to have sound psychometric properties for quantifying the severity of health, behavior and psychosocial problems concomitant to substance use in adolescents. Its utility for identifying yout[...]
Article : Périodique
The heritability of substance dependence (SD) liability is based on polymorphisms at the genes that are likely to be related to the function of the central nervous system. We have recently shown an association between the dopamine D5 receptor ge[...]
Article : Périodique
Sex differences in cortisol level and neurobehavioral disinhibition in children of substance abusers
This investigation determined the extent to which cortisol level, an index of HPA axis activity, covaries with neurobehavioral disinhibition. The sample consisted of 369 boys and 91 girls who were assigned to either a high average risk (HAR) gro[...]
Article : Périodique
A test of a theory positing a role of sexual maturation and behavioral self-regulation in the development of early onset substance use disorders (Tarter et al., 1999) was conducted. The rate of maturation in adolescent males across three timepoi[...]
Article : Périodique
This study prospectively examined the extent to which behavioral dysregulation in late childhood (10-12 years old) predicted daily cigarette smoking in mid-adolescence (age 16) in a sample of 208 subjects who had provided both baseline informati[...]
Article : Périodique
Suicide is the outcome of a discrete behavioral act which may precede, or emerge consequent to a substance use disorder (SUD). A question that has yet to be empirically addressed pertains to the extent to which SUD and suicide have a common liab[...]
Article : Périodique
This study examined the association between executive cognitive functioning (ECF), negative affectivity (NA) and drug use in adolescent males. Subjects were 250 boys, ages 15-17 years, with (FH+ n=90) and without (FH- n=160) a family history of [...]
Article : Périodique
M. G. DUNN ;
A. MEZZICH ;
JANISZEWSKI S. ;
L. KIRISCI ;
R. E. TARTER
|
Paternal and maternal models of transmission of child neglect were tested separately in 10-12 year old offspring of men with a substance use disorder (SUD) and psychiatrically normal men (n=156). The model hypothesizes that childhood neglect exp[...]
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