Buprenorphine/naloxone vs methadone for the treatment of opioid use disorder

B. NOSYK ; J. E. MIN ; F. HOMAYRA ; M. KURZ ; B. C. GUERRA-ALEJOS ; R. YAN ; M. PISKE ; S. R. SEAMAN ; P. BACH ; S. GREENLAND ; M. E. KARIM ; U. SIEBERT ; J. BRUNEAU ; P. GUSTAFSON ; K. KAMPMAN ; P. T. KORTHUIS ; T. LOUGHIN ; L. C. MCCANDLESS ; R. W. PLATT ; K. T. SCHNEPEL ; M. E. SOCIAS | 2024
Dans Journal of the American Medical Association (Vol.332, n°21, December 3, 2024) Article : Périodique

Key points: Question: Is buprenorphine/naloxone associated with lower risk of treatment discontinuation and mortality compared with methadone? Findings: In this population-based retrospective cohort study that included 30?891 individuals initi[...]

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Inability to access health and social services associated with mental health among people who inject drugs in a Canadian setting

L. WANG ; D. PANAGIOTOGLOU ; J. E. MIN ; K. DEBECK ; M. J. MILLOY ; T. KERR ; K. HAYASHI ; B. NOSYK | 2016
Dans Drug and Alcohol Dependence (Vol.168, November 2016) Article : Périodique

Background: People who inject drugs (PWID) face barriers to healthcare due to reasons including comorbidity. We evaluated access to health and social services by three of the most prevalent comorbid conditions among PWID: HIV, hepatitis C (HCV),[...]

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Opioid agonist treatment and risk of mortality during opioid overdose public health emergency: population based retrospective cohort study

L. A. PEARCE ; J. E. MIN ; M. PISKE ; H. ZHOU ; F. HOMAYRA ; A. SLAUNWHITE ; M. IRVINE ; G. MCGOWAN ; B. NOSYK | 2020
Dans British Medical Journal (Vol.368, n°8240, 4 April 2020) Article : Périodique

Objective: To compare the risk of mortality among people with opioid use disorder on and off opioid agonist treatment (OAT) in a setting with a high prevalence of illicitly manufactured fentanyl and other potent synthetic opioids in the illicit [...]

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