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Advancing toxicovigilance of recreational drugs, including new psychoactive substances, by using data from four European poison centres

A. KADER ; M. HERMANNS-CLAUSEN ; A. VAN RIEL ; K. FABER ; L. HONDEBRINK | 2025
Dans Clinical Toxicology (Vol.63, n°1, January 2025) Article : Périodique

INTRODUCTION: Common recreational drugs and new psychoactive substances pose challenges to public health. This study investigated the feasibility of merging cases of recreational drug poisoning reported to European poison centres. METHODS: Four[...]

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High incidence of signs of neuropathy and self-reported substance use disorder for nitrous oxide in patients intoxicated with nitrous oxide

J. J. NUGTEREN-VAN LONKHUYZEN ; L. VAN DER BEN ; I. S. VAN DEN HENGEL-KOOT ; D. W. DE LANGE ; A. VAN RIEL ; L. HONDEBRINK | 2023
Dans European Addiction Research (Vol.29, n°3, July 2023) Article : Périodique

INTRODUCTION: The number of patients with excessive nitrous oxide (N2O) use and neurological disorders has been rising, indicating an addictive potential of N2O. We studied the incidence of self-reported substance use disorder (SUD)-related symp[...]

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Monitoring new psychoactive substances (NPS) in The Netherlands: Data from the drug market and the Poisons Information Centre

L. HONDEBRINK ; J. J. NUGTEREN-VAN LONKHUYZEN ; D. VAN DER GOUWE ; T. M. BRUNT | 2015
Dans Drug and Alcohol Dependence (Vol.147, February 2015) Article : Périodique

Background: In recent years, the number of new psychoactive substances (NPS) appearing on the illicit drug market strongly increased. However, little is known about their toxic effects and risks. Therefore, we determined the most frequently occu[...]

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New psychoactive substances (NPS) in the Netherlands: occurrence in forensic drug samples, consumer drug samples and poisons center exposures between 2013 and 2017

L. HONDEBRINK ; J. J. NUGTEREN-VAN LONKHUYZEN ; C. C. HUNAULT ; J. VAN DEN BERG ; D. VAN DER GOUWE ; A. J. H. P. VAN RIEL | 2020
Dans Addiction (Vol.115, n°4, April 2020) Article : Périodique

Background and Aims: Although European-wide data on the new psychoactive substances (NPS) drug market are available, country-specific data are limited. We studied recent NPS trend data relative to all recreational drugs on the Dutch drug market.[...]

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Pharmacokinetics, pharmacodynamics and toxicology of new psychoactive substances (NPS): 2C-B, 4-fluoroamphetamine and benzofurans

J. J. NUGTEREN-VAN LONKHUYZEN ; A. J. H. P. VAN RIEL ; T. M. BRUNT ; L. HONDEBRINK | 2015
Dans Drug and Alcohol Dependence (Vol.157, December 2015) Article : Périodique

Background: Recently, the number of new psychoactive substances (NPS) appearing on the illicit drug market has shown a marked increase. Although many users perceive the risk of using NPS as medium or low, these substances can pose a serious heal[...]

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Synthetic cathinones and their potential interactions with prescription drugs

R. R. CONTRUCCI ; T. M. BRUNT ; F. INAN ; E. J. F. FRANSSEN ; L. HONDEBRINK | 2020
Dans Therapeutic Drug Monitoring (Vol.42, n°1, February 2020) Article : Périodique

Purpose: Substance use disorder often coexists with other psychiatric disorders, resulting in the simultaneous use of recreational and prescription drugs. The authors aimed to identify potential pharmacokinetic and pharmacodynamic interactions b[...]

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