Marijuana-based drugs: innovative therapeutics or designer drugs of abuse?

K. A. SEELY ; P. L. PRATHER ; L. P. JAMES ; J. H. MORAN | 2011
Dans Molecular Interventions (Vol.11, n°1, February 2011) Article : Périodique

The principal psychoactive component of marijuana, Δ9-tetrahydrocannabinol (THC), activates CB1 cannabinoid receptors (CB1Rs). Unfortunately, pharmacological research into the design of effective THC analogs has been hampered by psychiatric side[...]

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