The pharmacodynamic and pharmacokinetic profile of intranasal crushed buprenorphine and buprenorphine/naloxone tablets in opioid abusers

L. S. MIDDLETON ; P. A. NUZZO ; M. R. LOFWALL ; D. E. MOODY ; S. L. WALSH | 2011
Dans Addiction (Vol.106, n°8, August 2011) Article : Périodique

AIMS Sublingual buprenorphine and buprenorphine/naloxone are efficacious opioid dependence pharmacotherapies, but there are reports of their diversion and misuse by the intranasal route. The study objectives were to characterize and compare thei[...]

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