Cocaine vaccine for the treatment of cocaine dependence in methadone maintained patients: a randomized double bind placebo controlled efficacity trial

B. A. MARTELL ; F. M. ORSON ; J. POLING ; E. MITCHELL ; R. D. ROSSEN ; T. GARDNER ; T. R. KOSTEN | 2009
Périodique

CONTEXT. Cocaine dependence, which affects 2.5 million Americans annually, has no US Food and Drug Administration–approved pharmacotherapy. OBJECTIVES. To evaluate the immunogenicity, safety, and efficacy of a novel cocaine vaccine to treat coc[...]

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